概述

  • 产品名称Anti-HOOK2抗体
    参阅全部 HOOK2 一抗
  • 描述
    小鼠单克隆抗体to HOOK2
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment: LEESVQHVVM EAIQELMTKD TPDSLSPETY GNFDSQSRRY YFLSEEAEEG DELQQRCLDL ERQLMLLSEE KQSLAQENAG LRERMGRPEG EGTPGLTAKK , corresponding to amino acids 138-238 of Human HOOK2

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • 纯度Protein G purified
  • 克隆单克隆
  • 同种型IgG1
  • 轻链类型kappa
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab57108 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性HOOK2 is a member of the Hook protein family. Hook proteins are cytosolic coiled-coil proteins that contain conserved N-terminal domains, which attach to microtubules, and more divergent C-terminal domains, which mediate binding to organelles. HOOK2 localizes to the centrosome through all phases of the cell cycle. Interference with HOOK2 function results in the loss of the radial organization of microtubules suggesting that HOOK2 contributes to the establishment and maintenance of centrosomal structure and function. HOOK2 may contribute to the establishment and maintenance of the pericentrosomal localization of aggresomes by promoting the microtubule-based delivery of protein aggregates to pericentriolar aggresomes.
    • 细胞定位Cytoplasmic. Note=Associates with discrete punctate structure that correspond to neither early or late endosomes, lysosomes, multivesicular bodies (MVBs), Golgi complex, endoplasmic reticulum, nor mitochondria.
    • 数据库链接
    • 别名
      • A630054I03Rik antibody
      • FLJ26218 antibody
      • h hook2 antibody
      • hHK 2 antibody
      • hHK2 antibody
      • hhook 2 antibody
      • hhook2 antibody
      • HK 2 antibody
      • HK2 antibody
      • HOOK 2 antibody
      • hook homolog 2 (Drosophila) antibody
      • Hook homolog 2 antibody
      • MGC28586 antibody
      • MGC91008 antibody
      see all

    Anti-HOOK2 antibody 图像

    • Western blot against tagged recombinant protein immunogen using ab57108 HOOK2 antibody at 1ug/ml. Predicted band size of immunogen is 37 kDa

    Anti-HOOK2 antibody (ab57108)参考文献

    ab57108 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"