概述

  • 产品名称Anti-HOOK1抗体
    参阅全部 HOOK1 一抗
  • 描述
    兔多克隆抗体to HOOK1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Pig
  • 免疫原

    Synthetic peptide corresponding to a region within C terminal amino acids 464-513 (REVFIRLQHE NKMLRLQQEG SENERIEELQ EQLEQKHRKM NELETEQRLS) of Human HOOK1 (NP_056972).

  • 阳性对照
    • Human fetal heart lysate

性能

应用

Our Abpromise guarantee covers the use of ab122997 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 85 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Required for spermatid differentiation. Probably involved in the positioning of the microtubules of the manchette and the flagellum in relation to the membrane skeleton (By similarity). Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex).
  • 序列相似性Belongs to the hook family.
  • 细胞定位Cytoplasm > cytoskeleton. Cytoplasm. Localizes to the spermatid manchette during spermiogenesis but is not present in mature spermatozoa (By similarity). Localizes to punctate cytoplasmic foci which do not appear to overlap with early or late endosomes, the endoplasmic reticulum, the Golgi complex, multivesicular bodies (MVBs), lysosomes, or mitochondria. Often found in close association with microtubules.
  • Information by UniProt
  • 数据库链接
  • 别名
    • A930033L17Rik antibody
    • Abnormal spermatozoon head shape antibody
    • azh antibody
    • h-hook1 antibody
    • hHK1 antibody
    • HK1 antibody
    • HOOK 1 antibody
    • Hook homolog 1 (Drosophila) antibody
    • Hook1 antibody
    • HOOK1_HUMAN antibody
    • MGC10642 antibody
    • OTTHUMP00000010548 antibody
    • OTTMUSP00000008480 antibody
    • Protein Hook homolog 1 antibody
    • RP23-80B16.4 antibody
    see all

Anti-HOOK1 antibody 图像

  • Anti-HOOK1 antibody (ab122997) at 1 µg/ml + Human fetal heart lysate at 10 µg

    Predicted band size : 85 kDa

Anti-HOOK1 antibody (ab122997)参考文献

ab122997 has not yet been referenced specifically in any publications.

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