概述

  • 产品名称
  • 描述
    兔多克隆抗体to HOOK1
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Full length protein, corresponding to amino acids 1-728 of Human HOOK1 (NP_056972.1).

  • 阳性对照
    • Human pancreas and Mouse testis tissue lysates; HOOK1 transfected 293T cell line lysates

性能

应用

Our Abpromise guarantee covers the use of ab103533 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 85 kDa.

靶标

  • 功能
    Required for spermatid differentiation. Probably involved in the positioning of the microtubules of the manchette and the flagellum in relation to the membrane skeleton (By similarity). Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex).
  • 序列相似性
    Belongs to the hook family.
  • 细胞定位
    Cytoplasm > cytoskeleton. Cytoplasm. Localizes to the spermatid manchette during spermiogenesis but is not present in mature spermatozoa (By similarity). Localizes to punctate cytoplasmic foci which do not appear to overlap with early or late endosomes, the endoplasmic reticulum, the Golgi complex, multivesicular bodies (MVBs), lysosomes, or mitochondria. Often found in close association with microtubules.
  • Information by UniProt
  • 数据库链接
  • 别名
    • A930033L17Rik antibody
    • Abnormal spermatozoon head shape antibody
    • azh antibody
    • h-hook1 antibody
    • hHK1 antibody
    • HK1 antibody
    • HOOK 1 antibody
    • Hook homolog 1 (Drosophila) antibody
    • Hook1 antibody
    • HOOK1_HUMAN antibody
    • MGC10642 antibody
    • OTTHUMP00000010548 antibody
    • OTTMUSP00000008480 antibody
    • Protein Hook homolog 1 antibody
    • RP23-80B16.4 antibody
    see all

图片

  • Anti-HOOK1 antibody (ab103533) at 1/500 dilution + Human pancreas tissue lysate at 50 µg

    Predicted band size : 85 kDa
  • Anti-HOOK1 antibody (ab103533) at 1/500 dilution + Mouse testis tissue lysate at 50 µg

    Predicted band size : 85 kDa
  • All lanes : Anti-HOOK1 antibody (ab103533) at 1/500 dilution

    Lane 1 : HOOK1 transfected 293T cell line lysate
    Lane 2 : Non-transfected 293T cell line lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 85 kDa

实验方案

文献

ab103533 has not yet been referenced specifically in any publications.

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