Anti-HOMER3抗体(ab97438)
Key features and details
- Rabbit polyclonal to HOMER3
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-HOMER3抗体 -
描述
兔多克隆抗体to HOMER3 -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat -
免疫原
Recombinant protein fragment corresponding to a region within amino acids 55 and 275 of HOMER3 (AAH12113).
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阳性对照
- NT2D1 cell lysate
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab97438于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
1/500 - 1/3000. Predicted molecular weight: 40 kDa.
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说明 |
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WB
1/500 - 1/3000. Predicted molecular weight: 40 kDa. |
靶标
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功能
Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. Isoforms can be differently regulated and may play an important role in maintaining the plasticity at glutamatergic synapses. -
序列相似性
Belongs to the Homer family.
Contains 1 WH1 domain. -
结构域
The WH1 domain interacts with the PPXXF motif in GRM1, GRM5, RYR1, RYR2, ITPR1, SHANK 1 and SHANK3. -
细胞定位
Cytoplasm. Cell junction > synapse > postsynaptic cell membrane > postsynaptic density. Cell junction > synapse. Postsynaptic density of neuronal cells. - Information by UniProt
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数据库链接
- Entrez Gene: 9454 Human
- Entrez Gene: 26558 Mouse
- Entrez Gene: 29548 Rat
- Omim: 604800 Human
- SwissProt: Q9NSC5 Human
- SwissProt: Q99JP6 Mouse
- SwissProt: Q9Z2X5 Rat
- Unigene: 720208 Human
see all -
别名
- HOME3_HUMAN antibody
- HOMER 3 antibody
- Homer 3D protein antibody
see all
图片
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab97438 被引用在 1 文献中.
- Pu J et al. Long non-coding RNA HOMER3-AS1 drives hepatocellular carcinoma progression via modulating the behaviors of both tumor cells and macrophages. Cell Death Dis 12:1103 (2021). PubMed: 34815380