Anti-hnRNP U/p120抗体(ab122906)
Key features and details
- Rabbit polyclonal to hnRNP U/p120
- Suitable for: WB, ICC/IF
- Reacts with: Mouse, Human
- Isotype: IgG
概述
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产品名称
Anti-hnRNP U/p120抗体
参阅全部 hnRNP U/p120 一抗 -
描述
兔多克隆抗体to hnRNP U/p120 -
宿主
Rabbit -
特异性
ab122906 can recognize exogenous Myc tagged hnRNP U/p120 (vector expressed hnRNP U/p120) and endogenous hnRNP U/p120 (native). -
经测试应用
适用于: WB, ICC/IFmore details -
种属反应性
与反应: Mouse, Human -
免疫原
Recombinant fragment. This information is proprietary to Abcam and/or its suppliers.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at -20ºC. -
存储溶液
pH: 6
Preservative: 0.05% Sodium azide
Constituent: 99% Whole serum -
Concentration information loading...
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纯度
Whole antiserum -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab122906于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
1/1000 - 1/3000. Predicted molecular weight: 91 kDa.
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ICC/IF |
1/500 - 1/1000.
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说明 |
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WB
1/1000 - 1/3000. Predicted molecular weight: 91 kDa. |
ICC/IF
1/500 - 1/1000. |
靶标
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功能
Component of the CRD-mediated complex that promotes MYC mRNA stabilization. Binds to pre-mRNA. Has high affinity for scaffold-attached region (SAR) DNA. Binds to double- and single-stranded DNA and RNA. -
序列相似性
Contains 1 B30.2/SPRY domain.
Contains 1 SAP domain. -
翻译后修饰
Extensively phosphorylated.
Arg-733 and Arg-739 are dimethylated, probably to asymmetric dimethylarginine. -
细胞定位
Nucleus. Cytoplasm. Cell surface. Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Component of ribonucleosomes. Also found associated with the cell surface. - Information by UniProt
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数据库链接
- Entrez Gene: 3192 Human
- Entrez Gene: 51810 Mouse
- Omim: 602869 Human
- SwissProt: Q00839 Human
- SwissProt: Q8VEK3 Mouse
- Unigene: 106212 Human
- Unigene: 86589 Mouse
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别名
- Heterogeneous nuclear ribonucleoprotein U antibody
- hnRNP U antibody
- hnRNP U protein antibody
see all
图片
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Lanes 1-2 : anti Myc antibody
Lanes 3-4 : Anti-hnRNP U/p120 antibody (ab122906) at 1/1000 dilution
Lanes 1 & 3 : lysates from SAOS2 cells transfected with pRc/CMV vector
Lanes 2 & 4 : lysates from SAOS2 cells transfected with pRc/CMV vector expressing Myc tagged hnRNP U
Predicted band size: 91 kDaMyc - hnRNP U/p120: Exogenous Myc tagged hnRNP U/p120
hnRNP U/p120: endogenous hnRNP U/p120. -
Immunofuorescent analysis of hnRNP U/p120 expression using ab122906 in Mouse P19 neurons (left) and in cells with in situ extracted nuclear matrix (right). Note that hnRNP U is concentrated in intranuclear speckles throughout the nucleoplasm.
实验方案
数据表及文件
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Datasheet download
文献 (1)
ab122906 被引用在 1 文献中.
- Taniura H & Yoshikawa K Necdin interacts with the ribonucleoprotein hnRNP U in the nuclear matrix. J Cell Biochem 84:545-55 (2002). PubMed: 11813259