Anti-hnRNP M1-M4抗体(ab73888)

概述

  • 产品名称Anti-hnRNP M1-M4抗体
    参阅全部 hnRNP M1-M4 一抗
  • 描述
    兔多克隆抗体to hnRNP M1-M4
  • 经测试应用适用于: ELISA, WB, IHC-P, ICC/IFmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Synthetic peptide derived from the N-terminal region of human hnRNP M1-M4.

  • 阳性对照
    • WB: extracts from HT29 cells; IHC-P: human breast carcinoma tissue; ICC/IF: MCF7 cells.

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab73888 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/40000.
WB 1/500 - 1/1000. Predicted molecular weight: 78 kDa.
IHC-P 1/50 - 1/100.
ICC/IF 1/500 - 1/1000.

靶标

  • 功能Pre-mRNA binding protein in vivo, binds avidly to poly(G) and poly(U) RNA homopolymers in vitro. Involved in splicing. Acts as a receptor for carcinoembryonic antigen in Kupffer cells, may initiate a series of signaling events leading to tyrosine phosphorylation of proteins and induction of IL-1 alpha, IL-6, IL-10 and tumor necrosis factor alpha cytokines.
  • 序列相似性Contains 3 RRM (RNA recognition motif) domains.
  • 翻译后修饰Sumoylated.
  • 细胞定位Nucleus > nucleolus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CEA receptor antibody
    • CEAR antibody
    • DKFZp547H118 antibody
    • Heterogeneous nuclear ribonucleoprotein M antibody
    • Heterogeneous nuclear ribonucleoprotein M4 antibody
    • Heterogenous nuclear ribonucleoprotein M4 antibody
    • hnRNA binding protein M4 antibody
    • hnRNP M antibody
    • Hnrnpm antibody
    • HNRNPM4 antibody
    • HNRPM antibody
    • HNRPM_HUMAN antibody
    • HNRPM4 antibody
    • HTGR1 antibody
    • N acetylglucosamine receptor 1 antibody
    • NAGR1 antibody
    see all

Anti-hnRNP M1-M4 antibody 图像

  • All lanes : Anti-hnRNP M1-M4 antibody (ab73888) at 1/500 dilution

    Lane 1 : extracts from HT29 cells
    Lane 2 : extracts from HT29 cells with immunizing peptide at 5 µg

    Lysates/proteins at 20 µg per lane.


    Predicted band size : 78 kDa
    Observed band size : 85 kDa (why is the actual band size different from the predicted?)
  • Left: immunofluorescence analysis of MCF7 cells, using 1/500-1/1000 ab73888; Right: same after pre-incubation with the immunizing peptide.
  • Left: immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using 1/50-1/100 ab73888; Right: same, after per-incubation with the immunizing peptide.

Anti-hnRNP M1-M4 antibody (ab73888)参考文献

ab73888 has not yet been referenced specifically in any publications.

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