The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/100000. Detects a band of approximately 60 kDa (predicted molecular weight: 51 kDa).
Use at an assay dependent concentration.
1/100 - 1/250.
功能One of the major pre-mRNA-binding proteins. Binds tenaciously to poly(C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences. Can also bind poly(C) single-stranded DNA.
序列相似性Contains 3 KH domains.
翻译后修饰Arg-296 and Arg-299 are dimethylated, probably to asymmetric dimethylarginine.
细胞定位Cytoplasm. Nucleus > nucleoplasm. In case of ASFV infection, there is a shift in the localization which becomes predominantly nuclear.