概述

  • 产品名称Anti-hnRNP K抗体
    参阅全部 hnRNP K 一抗
  • 描述
    兔多克隆抗体to hnRNP K
  • 特异性ab74129 detects endogenous levels of total hnRNP K protein.
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Synthesized non phosphopeptide derived from human hnRNP K around the phosphorylation site of serine 284 (D-M-SP-P-R).

  • 阳性对照
    • Extracts from LOVO cells and RAW264.7 cells

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.02% Sodium Azide
    Constituents: 50% Glycerol, PBS (without Mg2+ and Ca2+), 150mM Sodium chloride, pH 7.4
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明The antibody was affinity purified from rabbit antiserum by affinity chromatography using epitope specific immunogen.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab74129 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 51 kDa.
ELISA 1/40000.

靶标

  • 功能One of the major pre-mRNA-binding proteins. Binds tenaciously to poly(C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences. Can also bind poly(C) single-stranded DNA.
  • 序列相似性Contains 3 KH domains.
  • 翻译后修饰Arg-296 and Arg-299 are dimethylated, probably to asymmetric dimethylarginine.
  • 细胞定位Cytoplasm. Nucleus > nucleoplasm. In case of ASFV infection, there is a shift in the localization which becomes predominantly nuclear.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CSBP antibody
    • dC stretch binding protein antibody
    • FLJ41122 antibody
    • Heterogeneous nuclear ribonucleoprotein K antibody
    • hnRNP K antibody
    • HNRNPK antibody
    • HNRPK antibody
    • HNRPK_HUMAN antibody
    • Transformation up regulated nuclear protein antibody
    • Transformation up-regulated nuclear protein antibody
    • Transformation upregulated nuclear protein antibody
    • TUNP antibody
    see all

Anti-hnRNP K antibody 图像

  • All lanes : Anti-hnRNP K antibody (ab74129) at 1/500 dilution

    Lane 1 : Extracts from LOVO cells with no peptide
    Lane 2 : Extracts from RAW264.7 cells with no peptide
    Lane 3 : Extracts from LOVO cells with peptide at 5 µg

    Lysates/proteins at 5 µg per lane.


    Predicted band size : 51 kDa
    Observed band size : 51 kDa

Anti-hnRNP K antibody (ab74129)参考文献

ab74129 has not yet been referenced specifically in any publications.

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