Anti-hnRNP A1 (isoform A1-A)抗体(ab123378)

概述

  • 产品名称Anti-hnRNP A1 (isoform A1-A)抗体
  • 描述
    兔多克隆抗体to hnRNP A1 (isoform A1-A)
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide:

    SSSQR

    , corresponding to a region around amino acids 190-194 of Human hnRNP A1 (isoform A1-A) (P09651).

  • 阳性对照
    • 293 cell extract

性能

应用

Our Abpromise guarantee covers the use of ab123378 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Detects a band of approximately 34, 39 kDa (predicted molecular weight: 39 kDa). Incubate membrane with diluted antibody in 5% nonfat milk, 1X TBS, 0.1% Tween-20 at 4°C with gentle shaking over night.

靶标

  • 功能Involved in the packaging of pre-mRNA into hnRNP particles, transport of poly(A) mRNA from the nucleus to the cytoplasm and may modulate splice site selection. May play a role in HCV RNA replication.
  • 序列相似性Contains 2 RRM (RNA recognition motif) domains.
  • 翻译后修饰Arg-194, Arg-206 and Arg-225 are dimethylated, probably to asymmetric dimethylarginine.
    Sumoylated.
  • 细胞定位Nucleus. Cytoplasm. Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Shuttles continuously between the nucleus and the cytoplasm along with mRNA. Component of ribonucleosomes. In the course of viral infection, colocalizes with HCV NS5B at speckles in the cytoplasm in a HCV-replication dependent manner.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Helix-destabilizing protein antibody
    • Heterogeneous nuclear ribonucleoprotein A1 antibody
    • HN RPA1L3 antibody
    • hnRNP A1 antibody
    • hnRNP core protein A1 antibody
    • HNRNPA1 antibody
    • M MGC102835 antibody
    • ROA1_HUMAN antibody
    • Single-strand RNA-binding protein antibody
    see all

Anti-hnRNP A1 (isoform A1-A) antibody 图像

  • Anti-hnRNP A1 (isoform A1-A) antibody (ab123378) at 1/500 dilution + 293 cell extract

    Predicted band size : 39 kDa

Anti-hnRNP A1 (isoform A1-A) antibody (ab123378)参考文献

ab123378 has not yet been referenced specifically in any publications.

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