概述

  • 产品名称Anti-HMGB4抗体
    参阅全部 HMGB4 一抗
  • 描述
    兔多克隆抗体to HMGB4
  • 特异性No cross reactivity with other proteins.
  • 经测试应用适用于: WB, ICCmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide corresponding to Human HMGB4 aa 24-41 (N terminal). The human HMGB4 is different to the related mouse and rat sequence by a single amino acid.
    Sequence:

    RNKFKEQQPNTYVGFKEF


    Database link: Q8WW32

  • 阳性对照
    • Rat testicle tissue lysis

性能

应用

Our Abpromise guarantee covers the use of ab65980 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 22 kDa (predicted molecular weight: 22 kDa).
ICC Use at an assay dependent dilution.

靶标

  • 相关性High Mobility Group (HMG) proteins, a group of chromosomal proteins common to all eukaryotes, bind DNA in a non-sequence-specific fashion to promote chromatin function and gene regulation, helping with transcription, replication, recombination, and DNA repair. HMGB4 is HMG2-like, isoform 2, high-mobility group box 4. This gene can be found on Chromosome 1. HMGB4 contains two HMG-box regions, and is found in a variety of eukaryotic chromosomal proteins. HMGB proteins are phosphorylated to various extents. The existence of differentially modified forms increases the number of distinct HMGB protein variants in plant chromatin that may be adapted to certain functions.
  • 细胞定位Nuclear
  • 数据库链接
  • 别名
    • High mobility group box 4 antibody
    • High mobility group protein B4 antibody
    • HMG2 like antibody

Anti-HMGB4 antibody 图像

  • All lanes : Anti-HMGB4 antibody (ab65980) at 1/2 dilution

    Lane 1 : Rat brain tissue lysate
    Lane 2 : Rat testicular tissue lysate
    Lane 3 : Jurkat whole cell lysate
    Lane 4 : HT1080 whole cell lysate


    Predicted band size : 22 kDa
    Observed band size : 22 kDa
  • Anti-HMGB4 antibody (ab65980) at 1 µg/ml + rat testicle tissue lysis at 30 µg

    Predicted band size : 22 kDa
    Observed band size : 22 kDa

Anti-HMGB4 antibody (ab65980)参考文献

ab65980 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab65980.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"