概述

  • 产品名称
    Anti-HMBOX1抗体
  • 描述
    兔多克隆抗体to HMBOX1
  • 经测试应用
    适用于: WB, IHC-P, ICC/IFmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Zebrafish
  • 免疫原

    Recombinant fragment corresponding to a region within amino acids 142-377 of Human HMBOX1 (NP_078843)

  • 阳性对照

性能

应用

Our Abpromise guarantee covers the use of ab97643 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/3000. Predicted molecular weight: 47 kDa.
IHC-P 1/100 - 1/500.
ICC/IF 1/100 - 1/200.

靶标

  • 功能
    Transcription factor. Isoform 1 acts as a transcriptional repressor. Isoform 4 has very low activity as a transcriptional repressor.
  • 组织特异性
    Ubiquitous. Detected in pancreas, brain, spleen, placenta, prostate, thymus, liver, heart, bone marrow, skeletal muscle, stomach, uterus, testis, kidney, ovary, and colon.
  • 序列相似性
    Contains 1 homeobox DNA-binding domain.
  • 细胞定位
    Nucleus. Cytoplasm. Predominantly detected in cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • FLJ21616 antibody
    • HMBOX1 antibody
    • HMBOX1A antibody
    • HMBX1_HUMAN antibody
    • HNF1LA antibody
    • homeobox containing 1 antibody
    • Homeobox containing protein 1 antibody
    • Homeobox-containing protein 1 antibody
    • homeobox-containing protein PBHNF antibody
    • PBHNF antibody
    see all

图片

  • Anti-HMBOX1 antibody (ab97643) at 1/1000 dilution + Raji whole cell lysate at 30 µg

    Predicted band size : 47 kDa
  • Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using ab97643 at 1/200 dilution. Lower image is merged with DNA probe.
  • Immunohistochemical analysis of paraffin-embedded SW480 xenograft using ab97643 at 1/500 dilution.

文献

This product has been referenced in:
  • Gong J  et al. miR-30c-1* promotes natural killer cell cytotoxicity against human hepatoma cells by targeting the transcription factor HMBOX1. Cancer Sci 103:645-52 (2012). WB ; Human . Read more (PubMed: 22320217) »

See 1 Publication for this product

客户评价及客户问答

There are currently no Customer reviews or Questions for ab97643.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

注册