Anti-HLTF抗体(ab3852)

概述

  • 产品名称Anti-HLTF抗体
    参阅全部 HLTF 一抗
  • 描述
    兔多克隆抗体to HLTF
  • 特异性Recognizes a region between residues 900 and 950 of human HTLF using the numbering for NCBI accession NP_620636.1 (GeneID 6596).
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Dog, Pig, Chimpanzee, Rhesus monkey, Gorilla, Orangutan, Platypus (Ornithorhynchus anatinus)
  • 免疫原

    Synthetic peptide (Human) - which represents a portion of human HLTF encoded in part by exons 23 and 24.

  • 阳性对照
    • Nuclear extract from HeLa cells.

性能

应用

Our Abpromise guarantee covers the use of ab3852 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/5000. Detects a band of approximately 115 kDa (predicted molecular weight: 110 kDa).

靶标

  • 功能Has both helicase and E3 ubiquitin ligase activities. Possesses intrinsic ATP-dependent nucleosome-remodeling activity; This activity may be required for transcriptional activation or repression of specific target promoters (By similarity). These may include the SERPINE1 and HIV-1 promoters and the SV40 enhancer, to which this protein can bind directly. Plays a role in error-free postreplication repair (PRR) of damaged DNA and maintains genomic stability through acting as a ubiquitin ligase for 'Lys-63'-linked polyubiquitination of chromatin-bound PCNA.
  • 组织特异性Expressed in brain, heart, kidney, liver, lung, pancreas, placenta and skeletal muscle.
  • 通路Protein modification; protein ubiquitination.
  • 序列相似性Belongs to the SNF2/RAD54 helicase family. RAD16 subfamily.
    Contains 1 helicase ATP-binding domain.
    Contains 1 helicase C-terminal domain.
    Contains 1 RING-type zinc finger.
  • 细胞定位Cytoplasm. Nucleus. Nucleus, nucleolus. Nucleus, nucleoplasm. Nuclear localization is stimulated by progesterone.
  • Information by UniProt
  • 数据库链接
  • 别名
    • DNA-binding protein/plasminogen activator inhibitor 1 regulator antibody
    • Helicase like transcription factor antibody
    • Helicase-like transcription factor antibody
    • HIP116 antibody
    • HIP116A antibody
    • HLTF 1 antibody
    • Hltf antibody
    • HLTF_HUMAN antibody
    • HLTF1 antibody
    • p113 antibody
    • RING finger protein 80 antibody
    • RNF80 antibody
    • SMARC A3 antibody
    • SMARCA 3 antibody
    • SMARCA3 antibody
    • SNF2-like 3 antibody
    • SNF2L3 antibody
    • Sucrose nonfermenting protein 2 like 3 antibody
    • Sucrose nonfermenting protein 2-like 3 antibody
    • SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily A member 3 antibody
    • SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a3 antibody
    • SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 antibody
    • ZBU 1 antibody
    • ZBU1 antibody
    see all

Anti-HLTF antibody 图像



  • Predicted band size : 110 kDa


    Sample: Nuclear Extract (20µg) from HeLa cells

    Antibody: Affinity purified Rabbit anti-SMARCA 3 (ab3852; 0.5µg/ml)

Anti-HLTF antibody (ab3852)参考文献

ab3852 has not yet been referenced specifically in any publications.

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The antibody recognizes a region between residues 900 and 950 of human HTLF using the numbering for NCBI accession NP_620636.1 (GeneID 6596).

EAGSPTIMLL SLKAGGVGLN LSAASRVFLM DPAWNPAAED QCFDRCHRLG
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"