Anti-HLA DR + HLA DP抗体[MEM-136] (Phycoerythrin) (ab77134)

概述

  • 产品名称Anti-HLA DR + HLA DP抗体[MEM-136] (Phycoerythrin)
    参阅全部 HLA DR + HLA DP 一抗
  • 描述
    小鼠单克隆抗体[MEM-136] to HLA DR + HLA DP (Phycoerythrin)
  • 偶联物Phycoerythrin. Ex: 488nm, Em: 575nm
  • 特异性ab77134 recognizes a common epitope on the beta chain of human HLA-DR and HLA-DP. It reacts with alpha/beta dimer as well as with dissociated beta subunit.
  • 经测试应用适用于: Flow Cytmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Tissue/ cell preparation (Human); PHA-activated peripheral blood lymphocytes.

  • 阳性对照
    • human blood cells
  • 常规说明

    Conjugates are made from highly purified antibodies (>95% by SDS-PAGE).

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C.
  • 存储溶液Preservative: 15mM Sodium Azide
    Constituents: 0.2% BSA (high-grade protease free), PBS
  • Concentration information loading...
  • 纯度Size exclusion
  • 纯化说明The protein A/G purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is then purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
  • 克隆单克隆
  • 克隆编号MEM-136
  • 同种型IgG1
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab77134 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt
  • 应用说明Flow Cyt: Use Neat: 20µl for 100µl whole blood or 106 cells in suspension.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性Human MHC class II antigens are transmembrane glycoproteins composed of an alpha (36 kDa) and a beta chain (27kDa) and are expressed primarily on antigen presenting cells. Human MHC class II genes are located in the HLA-D region that encodes at least 6 alpha and 10 beta chain genes. Three loci, DR, DQ and DP, encode the major products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells and therefore have a critical role in the initiation of the immune response. It has been shown that some autoimmune diseases are associated with certain class II alleles.
    • 细胞定位Cell Membrane; Single pass type I membrane protein
    • 数据库链接
    • 别名
      • HLA DP antibody
      • HLA DR antibody
      • MHC Class II antibody

    Anti-HLA DR + HLA DP antibody [MEM-136] (Phycoerythrin) (ab77134)参考文献

    ab77134 has not yet been referenced specifically in any publications.

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