Anti-HLA DR + HLA DP抗体[MEM-136] (FITC) (ab77237)

概述

  • 产品名称Anti-HLA DR + HLA DP抗体[MEM-136] (FITC)
    参阅全部 HLA DR + HLA DP 一抗
  • 描述
    小鼠单克隆抗体[MEM-136] to HLA DR + HLA DP (FITC)
  • 偶联物FITC. Ex: 493nm, Em: 528nm
  • 特异性ab77237 recognizes common epitope on beta-chain of human HLA-DR and HLA-DP. It reacts with alpha/beta dimer as well as with dissociated beta-subunit.
  • 经测试应用适用于: Flow Cytmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    PHA-activated peripheral blood lymphocytes.

  • 阳性对照
    • Human blood cells.
  • 常规说明

    The purified antibody is conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC and adjusted for direct use.

性能

应用

Our Abpromise guarantee covers the use of ab77237 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt
  • 应用说明Flow Cyt: Use 20µl for 106 cells or 100µl whole blood.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性Human MHC class II antigens are transmembrane glycoproteins composed of an alpha (36 kDa) and a beta chain (27kDa) and are expressed primarily on antigen presenting cells. Human MHC class II genes are located in the HLA-D region that encodes at least 6 alpha and 10 beta chain genes. Three loci, DR, DQ and DP, encode the major products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells and therefore have a critical role in the initiation of the immune response. It has been shown that some autoimmune diseases are associated with certain class II alleles.
    • 细胞定位Cell Membrane; Single pass type I membrane protein
    • 数据库链接
    • 别名
      • HLA DP antibody
      • HLA DR antibody
      • MHC Class II antibody

    Anti-HLA DR + HLA DP antibody [MEM-136] (FITC) (ab77237)参考文献

    This product has been referenced in:
    • Koch C  et al. T cell activation-associated epitopes of CD147 in regulation of the T cell response, and their definition by antibody affinity and antigen density. Int Immunol 11:777-86 (1999). Read more (PubMed: 10330283) »

    See 1 Publication for this product

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