Anti-HLA DR + HLA DP抗体[MEM-136] (ab8094)

概述

  • 产品名称Anti-HLA DR + HLA DP抗体[MEM-136]
    参阅全部 HLA DR + HLA DP 一抗
  • 描述
    小鼠单克隆抗体[MEM-136] to HLA DR + HLA DP
  • 特异性Common epitope on b-chain of human HLA-DR and HLA-DP. Reacts with alpha-beta dimer as well as with dissociated beta subunit.
  • 经测试应用适用于: Flow Cyt, IP, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Tissue, cells or virus corresponding to Human HLA DR + HLA DP.

性能

应用

Our Abpromise guarantee covers the use of ab8094 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt Use a concentration of 0.5 µg/ml. ab170190-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
IP Use at an assay dependent concentration.
WB Use at an assay dependent concentration. Use under non reducing condition. Detects a band of approximately 23 kDa.

靶标

  • 相关性Human MHC class II antigens are transmembrane glycoproteins composed of an alpha (36 kDa) and a beta chain (27kDa) and are expressed primarily on antigen presenting cells. Human MHC class II genes are located in the HLA-D region that encodes at least 6 alpha and 10 beta chain genes. Three loci, DR, DQ and DP, encode the major products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells and therefore have a critical role in the initiation of the immune response. It has been shown that some autoimmune diseases are associated with certain class II alleles.
  • 细胞定位Cell Membrane; Single pass type I membrane protein
  • 数据库链接
  • 别名
    • HLA DP antibody
    • HLA DR antibody
    • MHC Class II antibody

Anti-HLA DR + HLA DP antibody [MEM-136] (ab8094)参考文献

ab8094 has not yet been referenced specifically in any publications.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"