概述

  • 产品名称Anti-HLA DR + HLA DP抗体[HL-38]
    参阅全部 HLA DR + HLA DP 一抗
  • 描述
    小鼠单克隆抗体[HL-38] to HLA DR + HLA DP
  • 特异性The antibody also reacts with porcine MHC class II antigens (SLA-D gene products).
  • 经测试应用适用于: Flow Cyt, IP, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Tissue/ cell preparation (Human). (Burkitt lymphoma cell line Raji).

  • 表位This antibody binds to a common epitope on the b-chain of human HLA-DR and HLA-DP.

性能

应用

Our Abpromise guarantee covers the use of ab766 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt
IP
WB
  • 应用说明Flow Cyt: Use at an assay dependant concentration.
    IP: Use at an assay dependant concentration.
    WB: Use at an assay dependant concentration. Use under non-reducing conditions.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性Human MHC class II antigens are transmembrane glycoproteins composed of an alpha (36 kDa) and a beta chain (27kDa) and are expressed primarily on antigen presenting cells. Human MHC class II genes are located in the HLA-D region that encodes at least 6 alpha and 10 beta chain genes. Three loci, DR, DQ and DP, encode the major products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells and therefore have a critical role in the initiation of the immune response. It has been shown that some autoimmune diseases are associated with certain class II alleles.
    • 细胞定位Cell Membrane; Single pass type I membrane protein
    • 数据库链接
    • 别名
      • HLA DP antibody
      • HLA DR antibody
      • MHC Class II antibody

    Anti-HLA DR + HLA DP antibody [HL-38] (ab766)参考文献

    This product has been referenced in:
    • Horejsi­ V  et al. Monoclonal antibodies against human leucocyte antigens. I. Antibodies against beta-2-microglobulin, immunoglobulin kappa light chains, HLA-DR-like antigens, T8 antigen, T1 antigen, a monocyte antigen, and a pan-leucocyte antigen. Folia Biol (Praha) 32:12-25 (1986). Read more (PubMed: 2422063) »

    See 1 Publication for this product

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