概述

  • 产品名称Anti-HLA DMB抗体
    参阅全部 HLA DMB 一抗
  • 描述
    兔多克隆抗体to HLA DMB
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Rat
  • 免疫原

    Synthetic peptide corresponding to a region within N terminal amino acids 40-89 (FTYCISFNKD LLTCWDPEEN KMAPCEFGVL NSLANVLSQH LNQKDTLMQR) of Human HLA DMB (NP_002109).

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Constituents: 97% PBS, 2% Sucrose
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab125387 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use at an assay dependent dilution. Predicted molecular weight: 29 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 相关性HLA-DMB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta (DMB) chain, both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP (class II-associated invariant chain peptide) molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail.
  • 细胞定位Late endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Note=Localizes to late endocytic compartment. Associates with lysosome membranes.
  • 数据库链接
  • 别名
    • class II antigen HLA-DM beta chain antibody
    • class II histocompatibility antigen antibody
    • Class II histocompatibility antigen M beta chain antibody
    • D6S221E antibody
    • DMB antibody
    • HLA class II histocompatibility antigen DM beta chain antibody
    • HLA-DM histocompatibility type, beta chain antibody
    • M beta chain antibody
    • Major histocompatibility complex class II DM beta antibody
    • MHC class II antigen DMB antibody
    • MHC class II antigen HLA DM beta chain antibody
    • MHC class II HLA DMB antibody
    • OTTHUMP00000029257 antibody
    • Really interesting new gene 7 protein antibody
    • RING 7 antibody
    • RING7 antibody
    see all

Anti-HLA DMB antibody 图像

  • Anti-HLA DMB antibody (ab125387) at 1 µg/ml + Human placenta

    Predicted band size : 29 kDa

Anti-HLA DMB antibody (ab125387)参考文献

ab125387 has not yet been referenced specifically in any publications.

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