Anti-HLA Class II DR4抗体[8.L.335] (ab33903)

概述

  • 产品名称Anti-HLA Class II DR4抗体[8.L.335]
    参阅全部 HLA Class II DR4 一抗
  • 描述
    小鼠单克隆抗体[8.L.335] to HLA Class II DR4
  • 特异性This antibody reacts to HLA Class II DR4. It also crossreacts with the related proteins DR15 and DQ1. Specificity was determined at a 1/10 dilution by the microcytotoxicity test under standard conditions.
  • 经测试应用适用于: Microcytotoxicity testing, Flow Cyt, ICCmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length protein (Human)

  • 常规说明


    This antibody has been used for Cell typing and Chimerism studies.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Add glycerol to a final volume of 50% for extra stability and aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液Preservative: None
    Constituents: Ascites
  • Concentration information loading...
  • 纯度Ascites
  • Primary antibody说明This antibody has been used for Cell typing and Chimerism studies.
  • 克隆单克隆
  • 克隆编号8.L.335
  • 同种型IgM
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab33903 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Microcytotoxicity testing Use at an assay dependent concentration.

Add 0.9ml of 1% BSA in PBS to 100µl of X10 antibody stock.

Flow Cyt Use at an assay dependent concentration. ab91545-Mouse monoclonal IgM, is suitable for use as an isotype control with this antibody.
ICC Use at an assay dependent concentration.

靶标

  • 相关性HLA DR, like other MHC class II molecules, is a transmembrane glycoprotein composed of an alpha chain (36 kDa) and a beta chain (27 kDa). It is expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, thymic epithelial cells and activated T lymphocytes. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T helper cells. They therefore have a critical role in the initiation of the immune response.
  • 细胞定位Membrane; single pass type I membrane protein.
  • 数据库链接
  • 别名
    • HLA DR4 antibody
    • HLA DRA antibody
    • HLA DRB antibody
    • HLADR4 antibody
    • Major histocompatibility complex class II DR4 antibody
    • MHC class II antigen DR antibody
    see all

Anti-HLA Class II DR4 antibody [8.L.335] (ab33903)参考文献

ab33903 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your enquiry. It also crossreacts with the related proteins DR15 and DQ1. I have added this information to the datasheet. Thank you for bringing this to my attention. Please contact us again if you have further questions.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"