PE Anti-HLA Class I抗体[W6/32] (ab33257)
Key features and details
- PE Mouse monoclonal [W6/32] to HLA Class I
- Suitable for: Flow Cyt
- Reacts with: Cow, Cat, Human, Monkey, Baboon, Cynomolgus monkey, Macaque monkey
- Conjugation: PE. Ex: 488nm, Em: 575nm
- Isotype: IgG2a
Related conjugates and formulations
概述
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产品名称
PE Anti-HLA Class I抗体[W6/32]
参阅全部 HLA Class I 一抗 -
描述
PE小鼠单克隆抗体[W6/32] to HLA Class I -
宿主
Mouse -
偶联物
PE. Ex: 488nm, Em: 575nm -
特异性
This antibody recognises an antigenic determinant shared among products of the HLA A, B and C loci. -
经测试应用
适用于: Flow Cytmore details -
种属反应性
与反应: Cow, Cat, Human, Monkey, Baboon, Cynomolgus monkey, Macaque monkey -
免疫原
Tissue, cells or virus corresponding to Human HLA Class I. Purified human tonsil lymphocyte membranes.
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阳性对照
- Human peripheral blood lymphocytes.
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常规说明
50 tests will be supplied typically at a volume of 0.5ml at a concentration of 0.1mg/ml (concentration prior to conjugation).The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. -
存储溶液
Preservative: 0.09% Sodium azide
Constituents: PBS, 1% BSA, 5% Sucrose -
Concentration information loading...
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纯度
Protein G purified -
纯化说明
This antibody was purified from tissue culture supernatant. -
克隆
单克隆 -
克隆编号
W6/32 -
骨髓瘤
NS1/1-Ag4-1 -
同种型
IgG2a -
研究领域
相关产品
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Alternative Versions
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab33257于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
Flow Cyt |
Use 10µl for 106 cells.
ab91363 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody. Use 10µl to label 106 cells or 100µl whole blood. |
说明 |
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Flow Cyt
Use 10µl for 106 cells. ab91363 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody. Use 10µl to label 106 cells or 100µl whole blood. |
靶标
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相关性
HLA CLass I is involved in the presentation of foreign antigens to the immune system. -
细胞定位
Plasma membrane -
数据库链接
- Entrez Gene: 3105 Human
- Entrez Gene: 3133 Human
- Entrez Gene: 3134 Human
- Entrez Gene: 3135 Human
- Omim: 142800 Human
- SwissProt: O15506 Human
- SwissProt: P04439 Human
- SwissProt: P13747 Human
see all -
别名
- DKFZp686P19218 antibody
- EA1.2 antibody
- EA2.1 antibody
see all
数据表及文件
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SDS download
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Datasheet download
文献 (8)
ab33257 被引用在 8 文献中.
- Chen HC et al. Induction of metastatic cancer stem cells from the NK/LAK-resistant floating, but not adherent, subset of the UP-LN1 carcinoma cell line by IFN-?. Lab Invest 91:1502-13 (2011). PubMed: 21691263
- Hurton LV et al. Identifying candidate allogeneic NK-cell donors for hematopoietic stem-cell transplantation based on functional phenotype. Leukemia 24:1059-62 (2010). PubMed: 20164852
- Daniel D et al. Pathway of apoptosis induced in Jurkat T lymphoblasts by anti-HLA class I antibodies. Hum Immunol 65:189-99 (2004). PubMed: 15041157
- Andratschke M et al. MHC-class I antigen expression on micrometastases in bone marrow of patients with head and neck squamous cell cancer. Anticancer Res 23:1467-71 (2003). PubMed: 12820411
- Cabrera CM et al. Total loss of MHC class I in colorectal tumors can be explained by two molecular pathways: beta2-microglobulin inactivation in MSI-positive tumors and LMP7/TAP2 downregulation in MSI-negative tumors. Tissue Antigens 61:211-9 (2003). PubMed: 12694570
- Jaramillo A et al. Anti-HLA class I antibody binding to airway epithelial cells induces production of fibrogenic growth factors and apoptotic cell death: a possible mechanism for bronchiolitis obliterans syndrome. Hum Immunol 64:521-9 (2003). PubMed: 12691702
- Wu T et al. Detection of soluble HLA class I antigens by ELISA and determination of its reference value in population of Guangdong province. Di Yi Jun Yi Da Xue Xue Bao 22:931-3 (2002). PubMed: 12377624
- Pangault C et al. Lung macrophages and dendritic cells express HLA-G molecules in pulmonary diseases. Hum Immunol 63:83-90 (2002). PubMed: 11821155