PE Anti-HLA B7抗体[BB7.1] (ab33331)
Key features and details
- PE Mouse monoclonal [BB7.1] to HLA B7
- Suitable for: Flow Cyt
- Reacts with: Human, Monkey, Cynomolgus monkey
- Conjugation: PE. Ex: 488nm, Em: 575nm
- Isotype: IgG1
Related conjugates and formulations
概述
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产品名称
PE Anti-HLA B7抗体[BB7.1]
参阅全部 HLA B7 一抗 -
描述
PE小鼠单克隆抗体[BB7.1] to HLA B7 -
宿主
Mouse -
偶联物
PE. Ex: 488nm, Em: 575nm -
特异性
This antibody binds to the HLA B7 antigen and does not cross react with HLA B27 or other related HLA antigens. -
经测试应用
适用于: Flow Cytmore details -
种属反应性
与反应: Human, Monkey, Cynomolgus monkey -
免疫原
Full length protein corresponding to Human HLA B7. Papain solubilized HLA-B7 antigen.
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常规说明
This antibody can be used to distinguish true HLA B27 positives from false HLA B27 positives (i.e. HLA B7 positive) in the investigation of such diseases as ankylosing spondylitis and anterior uveitis.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. -
存储溶液
pH: 7.40
Preservative: 0.09% Sodium azide
Constituents: PBS, 1% BSA -
Concentration information loading...
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纯度
Protein G purified -
纯化说明
This antibody was purified from tissue culture supernatant. -
Primary antibody说明
This antibody can be used to distinguish true HLA B27 positives from false HLA B27 positives (i.e. HLA B7 positive) in the investigation of such diseases as ankylosing spondylitis and anterior uveitis. -
克隆
单克隆 -
克隆编号
BB7.1 -
同种型
IgG1 -
研究领域
相关产品
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Alternative Versions
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab33331于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
Flow Cyt |
Use at an assay dependent concentration.
(or 100ul whole blood). ab91357 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
说明 |
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Flow Cyt
Use at an assay dependent concentration. (or 100ul whole blood). ab91357 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
靶标
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相关性
HLA B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta 2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa. Hundreds of HLA B alleles have been described. -
细胞定位
Cell Membrane, single pass type I membrane protein. -
数据库链接
- Entrez Gene: 3106 Human
- Omim: 142830 Human
- SwissProt: P01889 Human
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别名
- Abacavir hypersensitivity, susceptibility to antibody
- Drug-induced liver injury due to flucloxacillin antibody
- HLA B antibody
see all
数据表及文件
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Datasheet download
文献 (1)
ab33331 被引用在 1 文献中.
- Viborg N et al. T cell recognition of novel shared breast cancer antigens is frequently observed in peripheral blood of breast cancer patients. Oncoimmunology 8:e1663107 (2019). PubMed: 31741759