Anti-HLA B27抗体[EP-4] (ab24094)

概述

  • 产品名称Anti-HLA B27抗体[EP-4]
    参阅全部 HLA B27 一抗
  • 描述
    小鼠单克隆抗体[EP-4] to HLA B27
  • 经测试应用适用于: ICCmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Tissue/ cell preparation. Lymphocytes from HLA-B27 individual.

  • 阳性对照
    • Blood
  • 常规说明


    ab24094 recognizes the HLA B27 cell surface antigen on human cells. It may be used to HLA type human lymphoctyes. Approximately 60% of patients with ankylosing spondylitis are HLA B27 positive. This reagent can be used to help identify this HLA haplotype in human lymphocytes.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: 0.05% Sodium azide
    Constituent: PBS
  • Concentration information loading...
  • 纯度Purified IgM
  • Primary antibody说明ab24094 recognizes the HLA B27 cell surface antigen on human cells. It may be used to HLA type human lymphoctyes. Approximately 60% of patients with ankylosing spondylitis are HLA B27 positive. This reagent can be used to help identify this HLA haplotype in human lymphocytes.
  • 克隆单克隆
  • 克隆编号EP-4
  • 同种型IgM
  • 轻链类型kappa
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab24094 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC Use at an assay dependent concentration.

For use with paraformaldehyde fixed cell suspensions or cytospins.

靶标

  • 相关性Involved in the presentation of foreign antigens to the immune system. HLA B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta 2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells.
  • 细胞定位Single-pass type 1 membrane protein
  • 数据库链接
  • 别名
    • HLAB antibody
    • Leukocyte antigen class I B antibody
    • Lymphocyte antigen antibody
    • Major histocompatibility complex class I B antibody
    • SPDA1 antibody
    see all

Anti-HLA B27 antibody [EP-4] (ab24094)参考文献

ab24094 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"