概述

  • 产品名称
    Anti-HIVEP2抗体[2418C2a]
  • 描述
    小鼠单克隆抗体[2418C2a] to HIVEP2
  • 宿主
    Mouse
  • 经测试应用
    适用于: Dot blot, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment of human HIVEP2 from near the C terminus.

  • 阳性对照
    • Recombinant human HIVEP2.

性能

应用

Our Abpromise guarantee covers the use of ab70599 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Dot blot
WB
  • 应用说明
    Dot: Use at an assay dependent dilution.
    WB: Use at an assay dependent dilution. Detects bands of approximately 35 and 39 kDa (predicted molecular weight: 269 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能
      This protein specifically binds to the DNA sequence 5'-GGGACTTTCC-3' which is found in the enhancer elements of numerous viral promoters such as those of SV40, CMV, or HIV1. In addition, related sequences are found in the enhancer elements of a number of cellular promoters, including those of the class I MHC, interleukin-2 receptor, somatostatin receptor II, and interferon-beta genes. It may act in T-cell activation.
    • 组织特异性
      Expressed in brain and skeletal muscle.
    • 序列相似性
      Contains 4 C2H2-type zinc fingers.
    • 细胞定位
      Nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • HIV EP2 antibody
      • HIV-EP2 antibody
      • HIVEP2 antibody
      • human immunodeficiency virus type I enhancer binding protein 2 antibody
      • Human immunodeficiency virus type I enhancer-binding protein 2 antibody
      • MBP 2 antibody
      • MBP-2 antibody
      • MHC binding protein 2 antibody
      • MHC-binding protein 2 antibody
      • MIBP1 antibody
      • SHN2 antibody
      • Transcription factor HIVEP2 antibody
      • ZAS2 antibody
      • ZEP2_HUMAN antibody
      • ZNF40B antibody
      see all

    图片

    • Anti-HIVEP2 antibody [2418C2a] (ab70599) + immunising recombinant protein

      Predicted band size: 269 kDa
      Observed band size: 35,39 kDa (why is the actual band size different from the predicted?)



      The molecular weight of the bands on the western blot does not correspond to the molecular weight of the natural protein because only a fragment of the protein was used.

    实验方案

    文献

    This product has been referenced in:
    • Bash-Imam Z  et al. Translational reprogramming of colorectal cancer cells induced by 5-fluorouracil through a miRNA-dependent mechanism. Oncotarget 8:46219-46233 (2017). Read more (PubMed: 28515355) »

    See 1 Publication for this product

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