Anti-HIVEP1抗体[2417C2 a] (ab58652)


  • 产品名称
    Anti-HIVEP1抗体[2417C2 a]
    参阅全部 HIVEP1 一抗
  • 描述
    小鼠单克隆抗体[2417C2 a] to HIVEP1
  • 宿主
  • 经测试应用
    适用于: WB, Dot blotmore details
  • 种属反应性
    与反应: Recombinant fragment
    预测可用于: Human
  • 免疫原

    Recombinant C terminal fragment of human HIVEP1



Our Abpromise guarantee covers the use of ab58652 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use at an assay dependent dilution. Predicted molecular weight: 297 kDa.
Dot blot Use at an assay dependent dilution.


  • 功能
    This protein specifically binds to the DNA sequence 5'-GGGACTTTCC-3' which is found in the enhancer elements of numerous viral promoters such as those of SV40, CMV, or HIV-1. In addition, related sequences are found in the enhancer elements of a number of cellular promoters, including those of the class I MHC, interleukin-2 receptor, and interferon-beta genes. It may act in T-cell activation. Involved in activating HIV-1 gene expression. Isoform 2 and isoform 3 also bind to the IPCS (IRF1 and p53 common sequence) DNA sequence in the promoter region of interferon regulatory factor 1 and p53 genes and are involved in transcription regulation of these genes. Isoform 2 does not activate HIV-1 gene expression. Isoform 2 and isoform 3 may be involved in apoptosis.
  • 序列相似性
    Contains 5 C2H2-type zinc fingers.
  • 结构域
    Contains two sets of 2 zinc-fingers, which are widely separated and recognize the same DNA sequence. There is a fifth zinc-finger in-between.
  • 细胞定位
    Cytoplasm. Nucleus and Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Cirhin interaction protein antibody
    • CIRIP antibody
    • CRYBP1 antibody
    • GAAP antibody
    • Gate keeper of apoptosis-activating protein antibody
    • HIV EP1 antibody
    • HIV-EP1 antibody
    • HIVEP 1 antibody
    • Hivep1 antibody
    • Human immunodeficiency virus type I enhancer binding protein 1 antibody
    • Human immunodeficiency virus type I enhancer-binding protein 1 antibody
    • Major histocompatibility complex binding protein 1 antibody
    • Major histocompatibility complex-binding protein 1 antibody
    • MBP 1 antibody
    • MBP-1 antibody
    • Positive regulatory domain II binding factor 1 antibody
    • Positive regulatory domain II-binding factor 1 antibody
    • PRDII BF1 antibody
    • PRDII-BF1 antibody
    • Schnurri 1 antibody
    • ZAS1 antibody
    • ZEP1_HUMAN antibody
    • Zinc finger protein 40 antibody
    • ZNF40 antibody
    • ZNF40A antibody
    see all


  • Anti-HIVEP1 antibody [2417C2 a] (ab58652) + immunising recombinant protein fragment

    Predicted band size: 297 kDa
    Observed band size: 34 kDa (why is the actual band size different from the predicted?)

    The molecular weight of the band on the western blot does not correspond to the molecular weight of the natural protein because only a fragment of the protein was used.



ab58652 has not yet been referenced specifically in any publications.


Gracias por tu respuesta, y por enviar las imágenes.

Dado que en nuestro laboratorio no se ha testado el anticuerpo con la proteína endógena, me temo que no tengo evidencias para asegurar que la banda a 34KDa corresponde ...

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Gracias por contactarnos.

Espero que no te importe que te conteste en castellano, ya que recientemente hemos inaugurado el Servicio Técnico en español. Si prefirieses seguir contactándonos en inglés, no dudes en co...

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Thank you very much for your interest in ab58652. To our knowledge, ab58652 has not been tested in immunohistochemistry on paraffin-embedded sections (IHC-P) yet. However, we do not see a reason why it should not work. Therefore, I can offer a disco...

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Thank you for contacting us. The immunogen is a C-terminal fragment within residues 2550 and the C-terminus of isoform 1 - based on the UniProt database entry for the human protein P15822. The exact epitope ...

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