HIV2 gp36肽(ab43147)

概述

描述

  • 性质Synthetic

技术指标

Our Abpromise guarantee covers the use of ab43147 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性Immunoreactive with all sera of HIV-2 infected individuals.
  • 应用

    ELISA

    Western blot

  • 形式Liquid
  • 补充说明

    Immunoreactive with all sera of HIV-2 infected individuals.

  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: H2O

常规信息

  • 别名
    • Gp36
    • HIV 2
    • Human immunodeficiency virus 2
  • 相关性HIV2 infections at present, are predominantly found in west Africa where it is the dominant form of HIV. Both HIV1 and HIV2 have the same modes of transmission and are associated with similar opportunistic infections and AIDS. In persons infected with HIV2, immunodeficiency seems to develop more slowly and to be milder, but as the disease advances, HIV2 infectiousness seems to increase. Little is known about the best approach to the clinical treatment and care of patients infected with HIV2. Some drugs used to treat HIV1 are ineffective. HIV1 and HIV2 have similar gag (viral core) and pol (polymerase) regions, they have relatively dissimilar env (envelope) regions. Owing to this lack of homology in the envelope region, there is little serologic cross-reactivity of the antibodies directed against the envelope antigens of both HIV1 and HIV2. The env gp36 ectodomain is highly conserved and elicits a type-specific antibody response. Hence, most licensed diagnostic assays incorporate gp36-derived antigens to detect HIV2 specific antibodies. It is becoming important to differentiate between single infection with either HIV1 or HIV2 and dual infection.

HIV2 gp36 peptide (ab43147)参考文献

ab43147 has not yet been referenced specifically in any publications.

Product Wall

Thank you for contacting us.

I received the following information from the lab to your questions:

1) Does it mean the peptide doesn't react with only HIV1 positivesera, and shows positive reaction with HIV2 positive sera?
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Thank you for contacting us.

I received the following information from the lab:

The peptide contains 23 AA. It has no homology to HIV-1, and no immunoreaction with HIV positive sera.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"