Anti-HIV1 gp120抗体(Biotin) (ab53937)

概述

  • 产品名称Anti-HIV1 gp120抗体(Biotin)
    参阅全部 HIV1 gp120 一抗
  • 描述
    山羊多克隆抗体to HIV1 gp120 (Biotin)
  • 偶联物Biotin
  • 特异性ab53937 is specific for gp120. It does not cross react with human T or B cells, human or bovine sera.
  • 经测试应用适用于: WB, ELISA, IHC-Fr, ICC/IFmore details
  • 种属反应性
    Reacts with Human Immunodeficiency Virus 1 Gp120.
  • 免疫原

    Full length native protein (purified) corresponding to HIV1 gp120. Purified native gp120 from strain IIIB.

性能

应用

Our Abpromise guarantee covers the use of ab53937 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use at an assay dependent dilution.
ELISA Use at an assay dependent dilution.
IHC-Fr Use at an assay dependent dilution.
ICC/IF Use at an assay dependent dilution.

靶标

  • 相关性HIV1 is equipped with the envelope gp160 glycoprotein for interaction with Langerhans cells (LCs) and dendritic cells (DCs), the members of the innate immune system, which confront the virus at the portal of virus entry in the human body. These cells are equipped with receptors by which they bind and endocytose the virus. The gp120 glycoprotein is used for binding to CD4 receptor and CCR5 co-receptor of T helper 2 (Th2) cells, and is able to induce FcepsilonRI(+) hematopoietic cells to produce IL4, which inactivates the host adaptive immune response.
  • 细胞定位Envelope surface glycoprotein.
  • 别名
    • Glycoprotein 120 antibody
    • gp120 antibody
    • SU antibody
    • Surface protein antibody

Anti-HIV1 gp120 antibody (Biotin) (ab53937)参考文献

This product has been referenced in:
  • Reuven EM  et al. The HIV-1 envelope transmembrane domain binds TLR2 through a distinct dimerization motif and inhibits TLR2-mediated responses. PLoS Pathog 10:e1004248 (2014). ICC/IF ; Mouse . Read more (PubMed: 25121610) »
  • Øynebråten I  et al. Increased generation of HIV-1 gp120-reactive CD8+ T cells by a DNA vaccine construct encoding the chemokine CCL3. PLoS One 9:e104814 (2014). Read more (PubMed: 25122197) »

See all 3 Publications for this product

Product Wall

Vielen Dank für Ihre Anfrage.

Leider muss ich Ihnen mitteilen, dass dies nicht zu unseren Standartmethoden gehört, wenn wir einen Antikörper entwickeln und charakterisieren.

Was Sie allerdings machen könnten, wenn ...

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Thank you for contacting us.

I am sorry that this antibody did not perform as stated on the datasheet. If payment has already been made on the original order and you wish to receive a refund, please ask your purchasing department to contact ou...

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Thank you for your enquiry and your interest in our products.
This antibody has not been tested against the HXB2 or JRFL strains yet. However, given the polyclonal nature of the antibody, there is a good chance it would react to these strains but ...

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Gracias por contactarnos.

Anti-HIV1 p24 [39/5.4A] (ab9071) tiene un precio de 370€ y se encuentra actualmente en stock, por lo que si lo pedís esta tarde o mañana (martes 12) a lo largo del día (antes de las 17 horas...

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Thank you for contacting us. This product is raised from purified native gp120 from strain IIIB. We have not sequenced the native protein used to raise this antibody. We have searched, and unfortunately, the gp120 sequence has not been submitted f...

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Thank you for contacting us.

Here is the sequence you requested:

gp120 [Human immunodeficiency virus 1]
GenBank: AAF69493.1
GenPept Graphics





>gi|7769646|gb|AAF69493.1|AF236860_1 gp120 [H...

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Thank you for your reply. To reduce the non-specific binding of your secondary antibody, you could: - Change your blocking agent, to either 5% non fat dried milk or 5% BSA. - Lower the concentration of the secondary antibody that you are using. - Add b...

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Thank you for contacting Abcam. I just want to make sure that I understand your negative control correctly; for your negative control, you added the secondary antibody only (no primary antibody) and that is the lane labeled 'gp120 negative'. Is that co...

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Thank you for your enquiry. These 4 products (ab21179, ab20105, ab20262, ab20008) were produced from the same goat antiserum. Catalog ab21179 is the purified antibody. The purified antibody is then labeled to produce the other catalog numbers: Bio...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"