The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
生物活性Immunoreactive with all sera of HIV type O infected individuals.
Immunoreactive with all sera of HIV type O infected individuals.
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Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
相关性The transmembrane protein gp41 (TM) acts as a class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes. Membranes fusion leads to delivery of the nucleocapsid into the cytoplasm.
HIV gp41 L peptide (ab43148)参考文献
has not yet been referenced specifically in any publications.