概述

描述

  • 性质Synthetic

技术指标

Our Abpromise guarantee covers the use of ab43148 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性Immunoreactive with all sera of HIV type O infected individuals.
  • 应用

    Western blot

    ELISA

  • 形式Liquid
  • 补充说明

    Immunoreactive with all sera of HIV type O infected individuals.

  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: H2O

常规信息

  • 别名
    • env
    • Glycoprotein 41
    • gp41
    • TM
    • Transmembrane protein
    see all
  • 相关性The transmembrane protein gp41 (TM) acts as a class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes. Membranes fusion leads to delivery of the nucleocapsid into the cytoplasm.
  • 细胞定位Cell membrane

HIV gp41 L peptide (ab43148)参考文献

ab43148 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"