Histone H4 (mono-methyl K20) Quantification试剂盒(Fluorometric) (ab115094)

概述

  • 产品名称Histone H4 (mono-methyl K20) Quantification试剂盒(Fluorometric)
    参阅全部 Histone H4 (K20 methylation) 试剂盒
  • 样品类型
    Tissue, Adherent cells, Suspension cells
  • 灵敏度
    1 ng/well
  • 范围
    10 ng/well - 2000 ng/well
  • 检测时间
    2h 30m
  • 种属反应性
    与反应: Mouse, Human
    预测可用于: all Mammals
  • 产品概述

    Methylation of histone H4 at lysine 20 is catalyzed by SET9 and SUV4.20h among other methyl transferases in mammalian cells. H4 (mono-methyl K20) is involved in the maintenance of the proper higher order structure of DNA and is consequently essential for chromosome condensation. It is also involved in gene silencing.

    Histone H4 (mono-methyl K20) Quantification Kit (Fluorometric) (ab115094) enables the user to measure global mono-methylation of histone H4K20. The global H4K20 mono-methylation can also be changed by inhibition or activation of HMTs, making quantitative detection of global mono-methyl histone H4K20 useful in developing a better understanding of epigenetic regulation of gene activation/repression and for developing HMT-targeted drugs. ab115094 is suitable for use with a variety of mammalian cells including fresh and frozen tissues, and cultured adherent and suspension cells.

  • 经测试应用适用于: Functional Studiesmore details

性能

    应用

    Our Abpromise guarantee covers the use of ab115094 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    应用 Ab评论 说明
    Functional Studies Use at an assay dependent concentration.

    实验方案

    Histone H4 (mono-methyl K20) Quantification Kit (Fluorometric) (ab115094)参考文献

    ab115094 has not yet been referenced specifically in any publications.

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