Histone H4 (acetyl K8) Quantification试剂盒(Fluorometric) (ab115119)

概述

  • 产品名称Histone H4 (acetyl K8) Quantification试剂盒(Fluorometric)
    参阅全部 Histone H4 (K8 acetylation) 试剂盒
  • 灵敏度
    0.4 ng/well
  • 范围
    20 ng/well - 5000 ng/well
  • 检测时间
    2h 30m
  • 种属反应性
    与反应: Mouse, Human
    预测可用于: all Mammals
  • 产品概述

    Acetylation of histones such histone H4 has been involved in the regulation of chromatin structure and the recruitment of transcription factors to gene promoters. HATs (histone acetyltransferases) and HDACs (histone deacetylases) play a critical role in controlling histone H4 actylation. Histone H4 (acetyl K8) reflects the hyperacetylated stated in histone H4 and strongly correlates with active state of genes. H4 (acetyl K8) is related to DNA repair and increased H4 (acetyl K8) has been observed in cancer and inflammatory diseases.

    Abcam's Histone H4 (acetyl K8) Quantification Kit (Fluorometric) (ab115119) allows the experimenter to measure global acetylation of histone H4K8 quickly and consistently. The kit is ready-to-use and provides all the essential components needed to carry out a successful assay experiment and it is suitable for specifically measuring global histone H4K8 acetylation using a variety of mammalian cells including fresh and frozen tissues, and cultured adherent and suspension cells.

  • 经测试应用适用于: Functional Studiesmore details

性能

    应用

    Our Abpromise guarantee covers the use of ab115119 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    应用 Ab评论 说明
    Functional Studies Use at an assay dependent concentration.

    实验方案

    Histone H4 (acetyl K8) Quantification Kit (Fluorometric) (ab115119)参考文献

    ab115119 has not yet been referenced specifically in any publications.

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