Histone H3 (pan-methyl K79) Quantification试剂盒(Fluorometric) (ab115090)

概述

  • 产品名称Histone H3 (pan-methyl K79) Quantification试剂盒(Fluorometric)
    参阅全部 Histone H3 (K79 methylation) 试剂盒
  • 测试
    1 x 96 test
  • 灵敏度
    0.4 ng/well
  • 范围
    5 ng/well - 2000 ng/well
  • 检测时间
    2h 30m
  • 种属反应性
    与反应: Mouse, Human
    预测可用于: all Mammals
  • 产品概述

    Methylation of histone H3 at lysine 79 is catalyzed by Dot1 in mammalian cells. Intergenic H3 (mono-methyl K79) is a mark of enhancer regions and may provide unique binding surfaces along the chromatin fibre to stabilize interactions between enhancers and their target promoters. H3 (di-methyl K79) and H3 (tri-methyl K79) are also widespread histone modifications and are associated with transcriptionally active genes. Increased global H3 (methyl K79) is also found to be involved in some pathological processes such as leukemogenesis in humans.

    Histone H3 (pan-methyl K79) Quantification Kit (Fluorometric) (ab115090) allows the user to specifically measure global mono-, di-, and tri-methylation of histone H3K79 fluorometrically using a variety of mammalian cells including fresh and frozen tissues, cultured adherent and suspension cells.

  • 经测试应用适用于: Functional Studiesmore details

性能

    应用

    Our Abpromise guarantee covers the use of ab115090 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    应用 Ab评论 说明
    Functional Studies Use at an assay dependent concentration.

    实验方案

    Histone H3 (pan-methyl K79) Quantification Kit (Fluorometric) (ab115090)参考文献

    ab115090 has not yet been referenced specifically in any publications.

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