Histone H3 (K9) Demethylase Activity Quantification Assay试剂盒(ab113458)

概述

  • 产品名称Histone H3 (K9) Demethylase Activity Quantification Assay试剂盒
    参阅全部 Histone Demethylase 试剂盒
  • 检测类型Enzyme activity
  • 检测时间
    1h 30m
  • 种属反应性
    与反应: Mouse, Human, Plants
    预测可用于: all Mammals, Other
  • 产品概述

    Methylation of histone H3 at lysine 9 (K9) mediates heterochromatin formation by forming a binding site for HP1 and also participates in silencing expression at euchromatic sites. H3(K9) demethylation is regulated by at least two classes of demethylases, JMJD1 (which can remove mono- and di-methylation from H3K9) and JMJD2 (which can remove trimethylation from H3K9).

    Histone H3 (K9) Demethylase Activity Quantification Assay Kit (ab113458) allows the user to measure activity/inhibition of H3K9 specific histone demethylases using cell/tissue extracts. The kit is ready-to-use and provides all the essential components needed for measuring histone demethylase H3K9 specific activity/inhibition from a broad range of species including mammalian cells/tissues, plants, and bacteria.

  • 经测试应用适用于: Functional Studiesmore details

性能

    应用

    Our Abpromise guarantee covers the use of ab113458 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    应用 Ab评论 说明
    Functional Studies Use at an assay dependent concentration.

    实验方案

    Histone H3 (K9) Demethylase Activity Quantification Assay Kit (ab113458)参考文献

    This product has been referenced in:
    • Galoian K  et al. Restoration of desmosomal junction protein expression and inhibition of H3K9-specific histone demethylase activity by cytostatic proline-rich polypeptide-1 leads to suppression of tumorigenic potential in human chondrosarcoma cells. Mol Clin Oncol 3:171-178 (2015). Functional Studies ; Human . Read more (PubMed: 25469290) »

    See 1 Publication for this product

    Product Wall

    There are currently no Abreviews or Questions for ab113458.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"