Histone H3 (acetyl K56) Quantification试剂盒(Fluorometric) (ab115115)

概述

  • 产品名称Histone H3 (acetyl K56) Quantification试剂盒(Fluorometric)
    参阅全部 Histone H3 (K56 acetylation) 试剂盒
  • 样品类型
    Adherent cells, Suspension cells
  • 灵敏度
    0.4 ng/well
  • 范围
    5 ng/well - 2000 ng/well
  • 检测时间
    2h 30m
  • 种属反应性
    与反应: Mouse, Human
    预测可用于: all Mammals
  • 产品概述

    Acetylation of histones such histone H3 has been involved in the regulation of chromatin structure and the recruitment of transcription factors to gene promoters. HATs (histone acetyltransferases) and HDACs (histone deacetylases) play a critical role in controlling histone H3 actylation. Histone H3 (acetyl K56) is cell cycle regulated, maintained upon replicative damage in a check-point manner and is essential for surviving DNA damage. H3 (acetyl K56) occurs normally during S-phase, and in absence of this modification, cellular survival following DNA damage is impaired.

    Abcam's Histone H3 (acetyl K56) Quantification Kit (Fluorometric) (ab115115) allows the experimenter to measure global acetylation of histone H3K56 quickly and consistently. The kit is ready-to-use and provides all the essential components needed to carry out a successful assay experiment and it is suitable for specifically measuring global histone H3K56 acetylation using a variety of mammalian cells including fresh and frozen tissues, and cultured adherent and suspension cells.

  • 经测试应用适用于: Functional Studiesmore details

性能

    应用

    Our Abpromise guarantee covers the use of ab115115 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    应用 Ab评论 说明
    Functional Studies Use at an assay dependent concentration.

    实验方案

    Histone H3 (acetyl K56) Quantification Kit (Fluorometric) (ab115115)参考文献

    ab115115 has not yet been referenced specifically in any publications.

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