概述

  • 产品名称
    Anti-Histone H1oo抗体
    参阅全部 Histone H1oo 一抗
  • 描述
    兔多克隆抗体to Histone H1oo
  • 经测试应用
    适用于: IHC-P, WBmore details
  • 种属反应性
    与反应: Mouse
  • 免疫原

    Synthetic peptide corresponding to Mouse Histone H1oo (C terminal).
    Database link: Q8VIK3

性能

应用

Our Abpromise guarantee covers the use of ab71580 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P Use at an assay dependent concentration.
WB 1/200 - 1/2000. Predicted molecular weight: 32 kDa.Can be blocked with Histone H1oo peptide (ab194535).

靶标

  • 功能
    May play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably through the perturbation of chromatin structure. Essential for meiotic maturation of germinal vesicle-stage oocytes. The somatic type linker histone H1c is rapidly replaced by H1oo in a donor nucleus transplanted into an oocyte. The greater mobility of H1oo as compared to H1c may contribute to this rapid replacement and increased instability of the embryonic chromatin structure. The rapid replacement of H1c with H1oo may play an important role in nuclear remodeling.
  • 组织特异性
    Oocyte-specific.
  • 序列相似性
    Belongs to the histone H1/H5 family.
    Contains 1 H15 (linker histone H1/H5 globular) domain.
  • 细胞定位
    Cytoplasm. Nucleus. Chromosome.
  • Information by UniProt
  • 数据库链接
  • 别名
    • H1 histone family member O oocyte specific antibody
    • H1FOO antibody
    • H1FOO_HUMAN antibody
    • Histone H1oo antibody
    • Oocyte-specific histone H1 antibody
    • Oocyte-specific linker histone H1 antibody
    • osH1 antibody
    see all

文献

This product has been referenced in:
  • Hou J  et al. Liraglutide, a long-acting GLP-1 mimetic, and its metabolite attenuate inflammation after intracerebral hemorrhage. J Cereb Blood Flow Metab 32:2201-10 (2012). Read more (PubMed: 22968320) »

See 1 Publication for this product

客户评价及客户问答

Application
Western blot
Loading amount
25 µg
Gel Running Conditions
Reduced Denaturing
Sample
Human Cell lysate - whole cell (Hela, Hep G2)
Specification
Hela, Hep G2
Blocking step
Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 23°C
Username

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提交于 Dec 26 2014

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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