Anti-Hirudin抗体[2D7] (ab17198)

概述

  • 产品名称Anti-Hirudin抗体[2D7]
  • 描述
    小鼠单克隆抗体[2D7] to Hirudin
  • 特异性The affinity (Kd) of this antibody for rHV2K47 is 4.5x10E-7 M
  • 经测试应用适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant full length protein (Human).

  • 表位The epitope of this antibody is located at the C-terminal end of hirudin.

性能

应用

Our Abpromise guarantee covers the use of ab17198 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA
WB
  • 应用说明ELISA: 1/2000.
    WB: Use at an assay dependent dilution. ab17198 reacts with hirudin in both reduced and unreduced forms. Detects a band of approximately 7 kDa.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性Hirudin is a highly effective and very specific anticoagulant which specifically inhibits formation of fibrin and activation of factors V, VIII and XIII by forming irreversible, noncovalent 1:1 complexes with a-thrombin. Hirudin is a 65 amino acid polypeptide, 7 kDa protein naturally originating from the medical leech Hirudo medicinalis. It is the most potent thrombin inhibitor known to date.
    • 细胞定位Secreted
    • 别名
      • Hirudin 1 antibody
      • Lepirudin antibody
      • Refludan antibody

    Anti-Hirudin antibody [2D7] (ab17198)参考文献

    ab17198 has not yet been referenced specifically in any publications.

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    Thank you for contacting Abcam.
    I have heard back from the lab and they have told me that ab17198reacts to the variant 2 form of Hirudin, not variant 1.
    I am sorry that I could not help you further in this matter, but if there is anything els...

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    Thank you for contacting us.

    We test ab17198 and ab36390 byaccessing their binding abilities to human thrombin and to complex of human thrombin with the thromobin inhibitor hirudin. We have not tested the antibodies in other species other th...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"