概述

  • 产品名称Anti-HIPK1抗体
    参阅全部 HIPK1 一抗
  • 描述
    兔多克隆抗体to HIPK1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 892-922 of Human HIPK1 (NP_689909.2, NP_852003.1, NP_938009.1, NP_938010.1).

  • 阳性对照
    • MCF7 cell line lysate.

性能

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应用

Our Abpromise guarantee covers the use of ab113028 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 131 kDa.

靶标

  • 功能May play a role as a corepressor for homeodomain transcription factors. Phosphorylates DAXX in response to stress, and mediates its translocation from the nucleus to the cytoplasm. May be involved in malignant squamous cell tumor formation.
  • 组织特异性Ubiquitously expressed with highest levels in skeletal muscle and heart. Overexpressed in breast cancer cell lines.
  • 序列相似性Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. HIPK subfamily.
    Contains 1 protein kinase domain.
  • 翻译后修饰Autophosphorylated. Phosphorylated and activated by JNK1.
  • 细胞定位Nucleus. Cytoplasm. Predominantly nuclear.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Hipk 1 antibody
    • Hipk1 antibody
    • HIPK1_HUMAN antibody
    • Homeodomain interacting protein kinase 1 antibody
    • Homeodomain interacting protein kinase 1 like protein antibody
    • Homeodomain-interacting protein kinase 1 antibody
    • Myak antibody
    • Nbak 2 antibody
    • Nbak2 antibody
    • Nuclear body associated kinase 2 antibody
    • Nuclear body associated kinase 2b antibody
    see all

Anti-HIPK1 antibody 图像

  • Lane 1 : Anti-HIPK1 antibody (ab113028) at 1/60 dilution
    Lane 2 : Anti-HIPK1 antibody (ab113028) at 1/250 dilution

    Lane 1 : MCF7 cell line lysate
    Lane 2 : MCF7 cell line lysate with blocking peptide

    Lysates/proteins at 12.5 µg per lane.


    Predicted band size : 131 kDa

Anti-HIPK1 antibody (ab113028)参考文献

ab113028 has not yet been referenced specifically in any publications.

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