概述

  • 产品名称Anti-HIP55抗体
    参阅全部 HIP55 一抗
  • 描述
    兔多克隆抗体to HIP55
  • 经测试应用适用于: IPmore details
    不适用于: WB
  • 种属反应性
    与反应: Human
    预测可用于: Chimpanzee, Gorilla
  • 免疫原

    Synthetic peptide corresponding to a region within amino acids 275-325 of Human HIP55 (NP_001014436.1).

  • 阳性对照
    • HeLa whole cell lysate

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.09% Sodium azide
    Constituent: 99% Tris citrate/phosphate
    Note: pH 7 to 8
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

相关产品

应用

Our Abpromise guarantee covers the use of ab118794 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IP Use at 2-10 µg/mg of lysate.
  • 应用说明Is unsuitable for WB.
  • 靶标

    • 功能Actin-binding adapter protein. May act as a common effector of antigen receptor-signaling pathways in leukocytes. Its association with dynamin suggests that it may also connect the actin cytoskeleton to endocytic function. Acts as a key component of the immunological synapse that regulates T-cell activation by bridging TCRs and the actin cytoskeleton to gene activation and endocytic processes. Binds to F-actin but is not involved in actin polymerization, capping or bundling. Does not bind G-actin.
    • 序列相似性Belongs to the ABP1 family.
      Contains 1 ADF-H domain.
      Contains 1 SH3 domain.
    • 结构域The SH3 domain mediates interaction with SHANK2, SHANK3 and PRAM1.
    • 翻译后修饰Degraded by caspases during apoptosis.
    • 细胞定位Cytoplasm > cytoskeleton. Cell projection > lamellipodium. Cortical cytoskeleton. Associates with lamellipodial actin.
    • Information by UniProt
    • 数据库链接
    • 别名
      • ABP1 antibody
      • Actin-binding protein 1 antibody
      • Cervical mucin associated protein antibody
      • Cervical mucin-associated protein antibody
      • Cervical SH3P7 antibody
      • CMAP antibody
      • Dbnl antibody
      • DBNL_HUMAN antibody
      • Drebrin F antibody
      • drebrin like antibody
      • Drebrin like protein antibody
      • Drebrin-F antibody
      • Drebrin-like protein antibody
      • HIP 55 antibody
      • HIP-55 antibody
      • HPK1 interacting protein of 55 kDa antibody
      • HPK1-interacting protein of 55 kDa antibody
      • SH3 domain containing protein 7 antibody
      • SH3 domain-containing protein 7 antibody
      • SH3P7 antibody
      • src homology 3 domain containing protein HIP 55 antibody
      see all

    Anti-HIP55 antibody 图像

    • Detection of HIP55 in Immunoprecipitates of HeLa whole cell lysates (1 mg for IP, 20% of IP loaded) using ab118794 at 6 µg/mg lysate for IP. For WB detection an anti-HIP55 antibody which recognizes an upstream epitope was used at 1 µg/ml.
      Detection: Chemiluminescence with an exposure time of 1 second.

    Anti-HIP55 antibody (ab118794)参考文献

    ab118794 has not yet been referenced specifically in any publications.

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