Anti-HIF-2-alpha抗体[ep190b] (ab8365)

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ab8365 被引用在 45 文献中.

  • Ling L  et al. Resveratrol activates endogenous cardiac stem cells and improves myocardial regeneration following acute myocardial infarction. Mol Med Rep 15:1188-1194 (2017). IHC-Fr ; Mouse . PubMed: 28138705
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  • Rodrigues T  et al. Methylglyoxal-induced glycation changes adipose tissue vascular architecture, flow and expansion, leading to insulin resistance. Sci Rep 7:1698 (2017). WB ; Rat . PubMed: 28490763
  • Sobhan PK  et al. ASK1 regulates the survival of neuroblastoma cells by interacting with TLX and stabilizing HIF-1a. Cell Signal 30:104-117 (2017). PubMed: 27890558
  • Jongen JMJ  et al. Downregulation of DNA repair proteins and increased DNA damage in hypoxic colon cancer cells is a therapeutically exploitable vulnerability. Oncotarget 8:86296-86311 (2017). PubMed: 29156796
  • Huang Q  et al. Androgen receptor increases hematogenous metastasis yet decreases lymphatic metastasis of renal cell carcinoma. Nat Commun 8:918 (2017). PubMed: 29030639
  • Szendroi A  et al. Opposite prognostic roles of HIF1a and HIF2a expressions in bone metastatic clear cell renal cell cancer. Oncotarget 7:42086-42098 (2016). IHC . PubMed: 27244898
  • Cimmino F  et al. CD55 is a HIF-2a marker with anti-adhesive and pro-invading properties in neuroblastoma. Oncogenesis 5:e212 (2016). IHC . PubMed: 27043658
  • Thom SR  et al. Measurements of CD34+/CD45-dim Stem Cells Predict Healing of Diabetic Neuropathic Wounds. Diabetes 65:486-97 (2016). PubMed: 26487786
  • Cimmino F  et al. Inhibition of hypoxia inducible factors combined with all-trans retinoic acid treatment enhances glial transdifferentiation of neuroblastoma cells. Sci Rep 5:11158 (2015). WB . PubMed: 26057707
  • Song W  et al. Infiltrating neutrophils promote renal cell carcinoma progression via VEGFa/HIF2a and estrogen receptor ß signals. Oncotarget 6:19290-304 (2015). WB, IHC-P . PubMed: 26079540
  • Trávnícek I  et al. Tissue Biomarkers in Predicting Response to Sunitinib Treatment of Metastatic Renal Cell Carcinoma. Anticancer Res 35:5661-6 (2015). Human . PubMed: 26408740
  • de Laplanche E  et al. Low glucose microenvironment of normal kidney cells stabilizes a subset of messengers involved in angiogenesis. Physiol Rep 3:N/A (2015). WB . PubMed: 25602014
  • Ng KP  et al. Physiologic hypoxia promotes maintenance of CML stem cells despite effective BCR-ABL1 inhibition. Blood 123:3316-26 (2014). IHC . PubMed: 24705490
  • Aesoy R  et al. Regulation of CDKN2B expression by interaction of Arnt with Miz-1--a basis for functional integration between the HIF and Myc gene regulatory pathways. Mol Cancer 13:54 (2014). WB ; Human . PubMed: 24618291
  • Xue G  et al. c-Myc-mediated repression of miR-15-16 in hypoxia is induced by increased HIF-2a and promotes tumor angiogenesis and metastasis by upregulating FGF2. Oncogene N/A:N/A (2014). PubMed: 24704828
  • Chavali PL  et al. TLX activates MMP-2, promotes self-renewal of tumor spheres in neuroblastoma and correlates with poor patient survival. Cell Death Dis 5:e1502 (2014). IHC . PubMed: 25356871
  • Pacak K  et al. New syndrome of paraganglioma and somatostatinoma associated with polycythemia. J Clin Oncol 31:1690-8 (2013). Human . PubMed: 23509317
  • Neumeister VM  et al. Quantitative assessment of effect of preanalytic cold ischemic time on protein expression in breast cancer tissues. J Natl Cancer Inst 104:1815-24 (2012). PubMed: 23090068
  • Bensellam M  et al. Glucose-induced O2 consumption activates hypoxia inducible factors 1 and 2 in rat insulin-secreting pancreatic beta-cells. PLoS One 7:e29807 (2012). WB . PubMed: 22235342
  • Xiang L  et al. Hypoxia-inducible factor-2a is associated with ABCG2 expression, histology-grade and Ki67 expression in breast invasive ductal carcinoma. Diagn Pathol 7:32 (2012). IHC-P ; Human . PubMed: 22452996
  • Bouquet F  et al. A DNA-dependent stress response involving DNA-PK occurs in hypoxic cells and contributes to cellular adaptation to hypoxia. J Cell Sci 124:1943-51 (2011). PubMed: 21576354
  • Shtutman M  et al. Function-based gene identification using enzymatically generated normalized shRNA library and massive parallel sequencing. Proc Natl Acad Sci U S A 107:7377-82 (2010). WB ; Human . PubMed: 20368428
  • McCord AM  et al. Physiologic oxygen concentration enhances the stem-like properties of CD133+ human glioblastoma cells in vitro. Mol Cancer Res 7:489-97 (2009). WB ; Human . PubMed: 19372578
  • Gimelli S  et al. The tumor suppressor gene TRC8/RNF139 is disrupted by a constitutional balanced translocation t(8;22)(q24.13;q11.21) in a young girl with dysgerminoma. Mol Cancer 8:52 (2009). IHC-P ; Human . PubMed: 19642973
  • Hervouet E  et al. HIF and reactive oxygen species regulate oxidative phosphorylation in cancer. Carcinogenesis 29:1528-37 (2008). PubMed: 18515279
  • Cleven AH  et al. Poorer outcome in stromal HIF-2 alpha- and CA9-positive colorectal adenocarcinomas is associated with wild-type TP53 but not with BNIP3 promoter hypermethylation or apoptosis. Br J Cancer 99:727-33 (2008). IHC-P ; Human . PubMed: 18728663
  • Favier J  et al. HIF2 alpha reduces growth rate but promotes angiogenesis in a mouse model of neuroblastoma. BMC Cancer 7:139 (2007). WB ; Human . PubMed: 17655754
  • Ioachim E  et al. Hypoxia-inducible factors HIF-1alpha and HIF-2alpha expression in bladder cancer and their associations with other angiogenesis-related proteins. Urol Int 77:255-63 (2006). PubMed: 17033215
  • Nakamura E  et al. Clusterin is a secreted marker for a hypoxia-inducible factor-independent function of the von Hippel-Lindau tumor suppressor protein. Am J Pathol 168:574-84 (2006). PubMed: 16436671
  • Shinojima T  et al. Renal cancer cells lacking hypoxia inducible factor (HIF)-1{alpha} expression maintain vascular endothelial growth factor expression through HIF-2{alpha} Carcinogenesis : (2006). PubMed: 16920734
  • Zimmer M  et al. Inhibition of hypoxia-inducible factor is sufficient for growth suppression of VHL-/- tumors. Mol Cancer Res 2:89-95 (2004). PubMed: 14985465
  • Marxsen JH  et al. Hypoxia-inducible factor-1 (HIF-1) promotes its degradation by induction of HIF-alpha-prolyl-4-hydroxylases. Biochem J 381:761-7 (2004). PubMed: 15104534
  • Grabmaier K  et al. Strict regulation of CAIX(G250/MN) by HIF-1alpha in clear cell renal cell carcinoma. Oncogene 23:5624-31 (2004). PubMed: 15184875
  • Pan Y  et al. p53 cannot be induced by hypoxia alone but responds to the hypoxic microenvironment. Oncogene 23:4975-83 (2004). PubMed: 15107830
  • Mekhail K  et al. HIF activation by pH-dependent nucleolar sequestration of VHL. Nat Cell Biol 6:642-7 (2004). PubMed: 15181450
  • Koike T  et al. Hypoxia induces adhesion molecules on cancer cells: A missing link between Warburg effect and induction of selectin-ligand carbohydrates. Proc Natl Acad Sci U S A 101:8132-7 (2004). PubMed: 15141079
  • Rathmell WK  et al. In vitro and in vivo models analyzing von Hippel-Lindau disease-specific mutations. Cancer Res 64:8595-603 (2004). PubMed: 15574766
  • Yoshimura H  et al. Prognostic impact of hypoxia-inducible factors 1alpha and 2alpha in colorectal cancer patients: correlation with tumor angiogenesis and cyclooxygenase-2 expression. Clin Cancer Res 10:8554-60 (2004). PubMed: 15623639
  • Harvey AJ  et al. Oxygen-regulated gene expression in bovine blastocysts. Biol Reprod 71:1108-19 (2004). PubMed: 15163614
  • Tissot van Patot MC  et al. Greater vascularity, lowered HIF-1/DNA binding, and elevated GSH as markers of adaptation to in vivo chronic hypoxia. Am J Physiol Lung Cell Mol Physiol 287:L525-32 (2004). PubMed: 15132953
  • Mohan S & Burk RD von Hippel-Lindau protein complex is regulated by cell density. Oncogene 22:5270-80 (2003). PubMed: 12917628
  • Koukourakis MI  et al. Hypoxia inducible factor (HIF-1a and HIF-2a) expression in early esophageal cancer and response to photodynamic therapy and radiotherapy. Cancer Res 61:1830-2 (2001). PubMed: 11280732
  • Blancher C  et al. Relationship of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha expression to vascular endothelial growth factor induction and hypoxia survival in human breast cancer cell lines. Cancer Res 60:7106-13 (2000). PubMed: 11156418
  • Talks KL  et al. The expression and distribution of the hypoxia-inducible factors HIF-1alpha and HIF-2alpha in normal human tissues, cancers, and tumor-associated macrophages. Am J Pathol 157:411-21 (2000). PubMed: 10934146