Anti-Hhip抗体[RM0090-8L46] (ab86450)

概述

  • 产品名称Anti-Hhip抗体[RM0090-8L46]
    参阅全部 Hhip 一抗
  • 描述
    大鼠单克隆抗体[RM0090-8L46] to Hhip
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse
  • 免疫原

    Recombinant fragment corresponding to the extracellular domain of mouse Hhip.

性能

  • 形式Lyophilised:Reconstitute the antibody with 200µl sterile PBS for an 0.5mg/ml solution.
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液Preservative: None
    Constituents: PBS
  • Concentration information loading...
  • 纯度Protein A purified
  • 纯化说明The IgG fraction of culture supernatant was purified by Protein A/G affinity chromatography and lyophilized from an 0.2 µm filtered solution.
  • 克隆单克隆
  • 克隆编号RM0090-8L46
  • 同种型IgG2
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab86450 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 79 kDa.

靶标

  • 功能Modulates hedgehog signaling in several cell types including brain and lung through direct interaction with members of the hedgehog family.
  • 组织特异性Widely expressed in fetal and adult tissues. Highest expression in adult heart, liver and pancreas, and in fetal kidney.
  • 序列相似性Belongs to the HHIP family.
    Contains 2 EGF-like domains.
  • 结构域A flexible loop interacts with the SHH zinc binding site and contributes to zinc binding.
  • 细胞定位Cytoplasm and Cell membrane. Secreted. The last 22 C-terminal amino acids may participate in cell membrane attachment.
  • Information by UniProt
  • 数据库链接
  • 别名
    • FLJ20992 antibody
    • FLJ90230 antibody
    • Hedgehog interacting protein antibody
    • Hedgehog-interacting protein antibody
    • hedgehoginteracting protein antibody
    • HHIP antibody
    • HHIP_HUMAN antibody
    • Hip antibody
    see all

Anti-Hhip antibody [RM0090-8L46] (ab86450)参考文献

ab86450 has not yet been referenced specifically in any publications.

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