概述

  • 产品名称Anti-Hhip抗体
    参阅全部 Hhip 一抗
  • 描述
    小鼠单克隆抗体to Hhip
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment: GDAKFGERNE GSGARRRRCL NGNPPKRLKR RDRRMMSQLE LLSGGEMLCG GFYPRLSCCL RSDSPGLGRL ENKIFSVTNN TECGKLLEEI KCALCSPHSQ , corresponding to amino acids 21-121 of Human Hhip

性能

应用

Our Abpromise guarantee covers the use of ab56406 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Modulates hedgehog signaling in several cell types including brain and lung through direct interaction with members of the hedgehog family.
    • 组织特异性Widely expressed in fetal and adult tissues. Highest expression in adult heart, liver and pancreas, and in fetal kidney.
    • 序列相似性Belongs to the HHIP family.
      Contains 2 EGF-like domains.
    • 结构域A flexible loop interacts with the SHH zinc binding site and contributes to zinc binding.
    • 细胞定位Cytoplasm and Cell membrane. Secreted. The last 22 C-terminal amino acids may participate in cell membrane attachment.
    • Information by UniProt
    • 数据库链接
    • 别名
      • FLJ20992 antibody
      • FLJ90230 antibody
      • Hedgehog interacting protein antibody
      • Hedgehog-interacting protein antibody
      • hedgehoginteracting protein antibody
      • HHIP antibody
      • HHIP_HUMAN antibody
      • Hip antibody
      see all

    Anti-Hhip antibody 图像



    • Predicted band size : 79 kDa
      Hhip antibody (ab56406) at 1ug/lane + HeLa cell lysate at 25ug/lane.

    Anti-Hhip antibody (ab56406)参考文献

    This product has been referenced in:
    • Kobune M  et al. Stromal cells expressing hedgehog-interacting protein regulate the proliferation of myeloid neoplasms. Blood Cancer J 2:e87 (2012). WB ; Human . Read more (PubMed: 22961059) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"