Anti-Hexokinase II抗体- N-terminal (ab71725)

概述

  • 产品名称Anti-Hexokinase II抗体- N-terminal
    参阅全部 Hexokinase II 一抗
  • 描述
    兔多克隆抗体to Hexokinase II - N-terminal
  • 经测试应用适用于: ELISA, IHC-P, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide from the N-terminal region of human Hexokinase II conjugated to KLH

  • 阳性对照
    • A375 cell lysate and human skeletal muscle tissue.

性能

应用

Our Abpromise guarantee covers the use of ab71725 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/1000.
IHC-P 1/50 - 1/100.
WB 1/100 - 1/500. Detects a band of approximately 102 kDa (predicted molecular weight: 102 kDa).

靶标

  • 组织特异性Predominant hexokinase isozyme expressed in insulin-responsive tissues such as skeletal muscle.
  • 通路Carbohydrate metabolism; hexose metabolism.
  • 序列相似性Belongs to the hexokinase family.
    Contains 2 hexokinase domains.
  • 结构域The N- and C-terminal halves of this hexokinase show extensive sequence similarity to each other. The catalytic activity is associated with the C-terminus while regulatory function is associated with the N-terminus. Each domain can bind a single glucose and Gluc-6-P molecule.
  • 细胞定位Mitochondrion outer membrane. Its hydrophobic N-terminal sequence may be involved in membrane binding.
  • Information by UniProt
  • 数据库链接
  • 别名
    • DKFZp686M1669 antibody
    • Hexokinase 2 antibody
    • Hexokinase 2 muscle antibody
    • Hexokinase type II antibody
    • Hexokinase-2 antibody
    • HK 2 antibody
    • HK II antibody
    • HK2 antibody
    • HKII antibody
    • HxK 2 antibody
    • HxK2 antibody
    • HXK2_HUMAN antibody
    • Muscle form hexokinase antibody
    see all

Anti-Hexokinase II antibody - N-terminal 图像

  • Anti-Hexokinase II antibody - N-terminal (ab71725) at 1/100 dilution + A375 cell lysate at 12.5 µg

    Predicted band size : 102 kDa
    Observed band size : 102 kDa
    Additional bands at : 65 kDa. We are unsure as to the identity of these extra bands.
  • ab71725 at 1/50 dilution, staining Hexokinase II in human skeletal muscle by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue, followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-Hexokinase II antibody - N-terminal (ab71725)参考文献

ab71725 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab71725.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"