概述

  • 产品名称
  • 描述
    兔多克隆抗体to HEXIM2
  • 经测试应用
    适用于: IPmore details
    不适用于: WB
  • 种属反应性
    与反应: Human
    预测可用于: Chimpanzee, Gorilla, Orangutan
  • 免疫原

    Synthetic peptide, corresponding to a region between amino acids 1-50 of Human HEXIM2 (NP_653209.1)

  • 阳性对照
    • HeLa whole cell lysate

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液
    pH: 7.50
    Preservative: 0.09% Sodium azide
    Constituent: 99% Tris citrate/phosphate
    Note: 7 to 8
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab112041 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IP Use at 2-5 µg/mg of lysate.
  • 应用说明
    Is unsuitable for WB.
  • 靶标

    • 功能
      Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation.
    • 组织特异性
      Ubiquitously expressed with higher expression in testis. HEXIM1 and HEXIM2 are differentially expressed.
    • 序列相似性
      Belongs to the HEXIM family.
    • 结构域
      The coiled-coil domain mediates oligomerization.
    • 细胞定位
      Nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Hexamethylene bis-acetamide-inducible protein 2 antibody
      • Hexamthylene bis-acetamide inducible 2 antibody
      • HEXI2_HUMAN antibody
      • hexim 2 antibody
      • HEXIM2 antibody
      • L3 antibody
      • Protein HEXIM2 antibody
      see all

    Anti-HEXIM2 antibody 图像

    • Detection of HEXIM2 by Western Blot of Immunprecipitate.
      ab112041 at 1µg/ml staining HEXIM2 in HeLa whole cell lysate immunoprecipitated using ab112041 at 6µg/mg lysate (1 mg/IP; 20% of IP loaded/lane). Detection: Chemiluminescence with exposure time of 30 seconds.

    Anti-HEXIM2 antibody (ab112041)参考文献

    ab112041 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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