概述

  • 产品名称Anti-HES6抗体
    参阅全部 HES6 一抗
  • 描述
    兔多克隆抗体to HES6
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    KLH conjugated synthetic peptide designed between amino acids 13~42 from the N-terminal region of Human HES6.

  • 阳性对照
    • MCF7 cell line lysate.

性能

应用

Our Abpromise guarantee covers the use of ab102823 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 24 kDa.

靶标

  • 相关性HES6 is a transcription cofactor that iteself does not bind to DNA but suppresses both HES1-mediated N box-dependent transcriptional repression and binding of HES1 to E box sequences. It also suppresses HES1-mediated inhibition of the heterodimer formed by ASCL1/MASH1 and TCFEA2/E47, allowing ASCL1 and TCFEA2 to upregulate transcription in its presence. HES6 appears to have novel functions in tumour and cancer cell lines, although these have not yet been elucidated fully.
  • 细胞定位Nuclear
  • 数据库链接
  • 别名
    • bHLHb41 antibody
    • bHLHc23 antibody
    • C HAIRY1 antibody
    • Class B basic helix-loop-helix protein 41 antibody
    • Hairy and enhancer of split 6 antibody
    • HES 6 antibody
    • Transcription cofactor HES6 antibody
    see all

Anti-HES6 antibody 图像

  • Anti-HES6 antibody (ab102823) at 1/100 dilution + MCF7 cell line lysate at 35 µg

    Predicted band size : 24 kDa

Anti-HES6 antibody (ab102823)参考文献

ab102823 has not yet been referenced specifically in any publications.

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