概述

性能

应用

Our Abpromise guarantee covers the use of ab57396 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Transcriptional repressor of genes that require a bHLH protein for their transcription.
    • 组织特异性Expressed in placenta, pancreatic cancer, colon cancer with RER, cervical cancer, and in head and neck tumors.
    • 序列相似性Contains 1 bHLH (basic helix-loop-helix) domain.
      Contains 1 Orange domain.
    • 结构域Has a particular type of basic domain (presence of a helix-interrupting proline) that binds to the N-box (CACNAG), rather than the canonical E-box (CANNTG).
      The C-terminal WRPW motif is a transcriptional repression domain necessary for the interaction with Groucho/TLE family members, transcriptional corepressors recruited to specific target DNA by Hairy-related proteins.
    • 细胞定位Nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • antibody
      • bHLHb40 antibody
      • Class B basic helix loop helix protein 40 antibody
      • Class B basic helix-loop-helix protein 40 antibody
      • Hairy and enhancer of split 2 (Drosophila) antibody
      • Hairy and enhancer of split 2 antibody
      • Hes2 antibody
      • HES2_HUMAN antibody
      • Transcription factor HES 2 antibody
      • Transcription factor HES-2 antibody
      see all

    Anti-HES2 antibody 图像

    • Western blot against tagged recombinant protein immunogen using ab57396 HES2 antibody at 1ug/ml. Predicted band size of immunogen is 34 kDa

    Anti-HES2 antibody (ab57396)参考文献

    ab57396 has not yet been referenced specifically in any publications.

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