概述

  • 产品名称
  • 描述
    兔多克隆抗体to HERC6
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Pig
  • 免疫原

    Synthetic peptide corresponding to a region within N terminal amino acids 143-192 (LSKDSQVFSW GKNSHGQLGL GKEFPSQASP QRVRSLEGIP LAQVAAGGAH) of Human HERC6 (NP_060382).

性能

应用

Our Abpromise guarantee covers the use of ab99173 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 115 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能
    E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
  • 组织特异性
    Detected in brain, heart, placenta and testis.
  • 通路
    Protein modification; protein ubiquitination.
  • 序列相似性
    Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain.
    Contains 5 RCC1 repeats.
  • 发展阶段
    Expressed in fetal brain.
  • 细胞定位
    Cytoplasm > cytosol.
  • Information by UniProt
  • 数据库链接
  • 别名
    • EC 6.3.2. antibody
    • FLJ20637 antibody
    • HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 antibody
    • HECT domain and RCC1 like domain containing protein 6 antibody
    • HECT domain and RCC1-like domain 6 antibody
    • HECT domain and RCC1-like domain-containing protein 6 antibody
    • Hect domain and RLD 6 antibody
    • HERC 6 antibody
    • HERC6 antibody
    • HERC6_HUMAN antibody
    • Potential ubiquitin ligase antibody
    • Probable E3 ubiquitin protein ligase HERC6 antibody
    • Probable E3 ubiquitin-protein ligase HERC6 antibody
    see all

图片



  • Predicted band size : 115 kDa
    Western blot analysis of ACHN cell lysate labeling HERC6 with ab99173 at 1µg/ml.

实验方案

文献

ab99173 has not yet been referenced specifically in any publications.

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