概述
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产品名称Anti-Hephaestin抗体- Carboxyterminal end
参阅全部 Hephaestin 一抗 -
描述兔多克隆抗体to Hephaestin - Carboxyterminal end
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宿主Rabbit
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经测试应用适用于: IHC-FoFr, ELISA, IHC-FrFl, WBmore details
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种属反应性与反应: Mouse, Rat, Recombinant fragment
预测可用于: Human
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免疫原
Synthetic peptide corresponding to C terminal residues of human Hephaestin precursor
性能
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形式Liquid
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存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
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存储溶液Preservative: 0.01% Sodium Azide
Constituents: 50% Glycerol, PBS -
Concentration information loading... -
纯度Immunogen affinity purified
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克隆多克隆
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同种型IgG
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研究领域
相关产品
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Compatible Secondaries
应用
Our Abpromise guarantee covers the use of ab56042 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IHC-FoFr | Use at an assay dependent concentration. | |
| ELISA | Use at an assay dependent concentration. | |
| IHC-FrFl | Use at an assay dependent concentration. | |
| WB | Use a concentration of 1 µg/ml. Predicted molecular weight: 130 kDa. for 2 hours. This antibody has been tested in Western blot against the recombinant peptide used as an immunogen. We have no data on detection of endogenous protein. |
靶标
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功能May function as a ferroxidase for ferrous (II) to ferric ion (III) conversion and may be involved in copper transport and homeostasis. Implicated in iron homeostasis and may mediate iron efflux associated to ferroportin 1.
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组织特异性Detected in breast, colon, bone trabecular cells and fibroblasts.
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序列相似性Belongs to the multicopper oxidase family.
Contains 6 plastocyanin-like domains. -
细胞定位Membrane.
- Information by UniProt
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数据库链接
- Entrez Gene: 9843 Human
- Entrez Gene: 15203 Mouse
- Entrez Gene: 117240 Rat
- Omim: 300167 Human
- SwissProt: Q9BQS7 Human
- SwissProt: Q9Z0Z4 Mouse
- SwissProt: Q920H8 Rat
- Unigene: 31720 Human
see all -
别名
- CPL antibody
- Heph antibody
- HEPH_HUMAN antibody
- Hephaestin antibody
图片
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Immunohistochemistry (PFA perfusion fixed frozen sections) - Anti-Hephaestin antibody - Carboxyterminal end (ab56042)This image was taken from an abreview submitted by Ruma Raha-Chowdhury.IHC-FoFr image of ab56042 staining of Hephaestin in mouse duodenum. Adult mouse was perfused with 4% PFA in 0.1M PBS and duodenal tissue was frozen sectioned. The sections were incubated with ab56042 (1:500) for one hour at 24°C, followed by Alexa Fluor 488 conjugated secondary antibody.
文献
ab56042 has not yet been referenced specifically in any publications.
客户评价及客户问答
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"