丙型肝炎病毒genotype 3a NS5 protein (ab68626)

概述

  • 产品名称丙型肝炎病毒genotype 3a NS5 protein
  • 蛋白长度Full length protein
  • 描述
    Recombinant丙型肝炎病毒genotype 3a NS5 protein

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • 额外的序列信息The E.coli derived recombinant protein fused to a GST tag contains the HCV NS5 Genotype 3 immunodominant regions.

技术指标

Our Abpromise guarantee covers the use of ab68626 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性ab68626 is immunoreactive with sera of HCV-infected individuals.
  • 应用

    Western blot

    ELISA

  • 纯度> 95 % SDS-PAGE.
    ab68626 was purified by a proprietary chromatographic technique.
  • 形式Liquid
  • 补充说明

    Immunoreactive with sera of HCV-infected individuals.

  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 50% Glycerol, 1.5M Urea, 25mM Tris HCl, 1mM EDTA

常规信息

  • 别名
    • HCV NS5
    • Hepatitis C virus NS5
    • Non structural protein 5A
    • NS5A
    • p56
    see all
  • 相关性HCV is classified into the genus Hepacivirus of the family Flaviviridae. Like all the members of the family, HCV is an enveloped, single-stranded, positive-sense RNA virus. Its genome (about 9600 nt) is flanked at both termini by conserved, highly structured non-translated regions (NTRs) and encodes a polyprotein precursor (about 3000 aa), which is proteolytically processed by host and viral proteases to produce the structural (core, E1, E2 and p7) and non-structural (NS2, NS3, NS4A, NS4B, NS5A and NS5B) proteins of the virus. Recently, an additional protein has been identified, whose function remains unknown. NS5A is a ~56 kDa pleiotropic protein with key roles in both viral RNA replication and modulation of the physiology of the host cell. It's exact role is not currently known (2008). NS5B RNA-dependant RNA polymerase is responsible for replication of the hepatitis C viral genome, and is currently a principal target for chemotherapeutic inhibition of HCV replication.

Hepatitis C Virus genotype 3a NS5 protein (ab68626)参考文献

ab68626 has not yet been referenced specifically in any publications.

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