抗丙型肝炎病毒Core Antigen抗体[6A1] (ab2582)
Key features and details
- Mouse monoclonal [6A1] to Hepatitis C Virus Core Antigen
- Suitable for: ELISA, IP
- Reacts with: Hepatitis C virus
- Isotype: IgG2a
Related conjugates and formulations
概述
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产品名称
抗丙型肝炎病毒Core Antigen抗体[6A1]
参阅全部 Hepatitis C Virus Core Antigen 一抗 -
描述
小鼠单克隆抗体[6A1] to丙型肝炎病毒Core Antigen -
宿主
Mouse -
特异性
This antibody is specific for Hepatitis C Core Antigen. -
经测试应用
适用于: ELISA, IPmore details -
种属反应性
与反应: Hepatitis C virus -
免疫原
Recombinant fragment, corresponding to amino acids 2-80 of Hepatitis C Virus Core Antigen
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表位
This antibody recognises amino acid residues 1-80 of Hepatitis C Core Antigen. -
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.20
Preservative: 0.01% Sodium azide -
Concentration information loading...
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克隆
单克隆 -
克隆编号
6A1 -
骨髓瘤
unknown -
同种型
IgG2a -
轻链类型
unknown -
研究领域
相关产品
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Alternative Versions
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Compatible Secondaries
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Isotype control
应用
应用 | Ab评论 | 说明 |
---|---|---|
ELISA |
1/10000.
|
|
IP |
Use at an assay dependent concentration.
|
说明 |
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ELISA
1/10000. |
IP
Use at an assay dependent concentration. |
靶标
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相关性
The hepatitis C virus (HCV) core protein represents the first 191 amino acids of the viral precursor polyprotein and is cotranslationally inserted into the membrane of the endoplasmic reticulum. Hepatitis C virus (HCV) core is a viral structural protein; it also participates in some cellular processes, including transcriptional regulation. However the mechanisms of core-mediated transcriptional regulation remain poorly understood. Hepatitis C virus (HCV) core protein is thought to contribute to HCV pathogenesis through its interaction with various signal transduction pathways. In addition, HCV core antigen is a recently developed marker of hepatitis C infection. The HCV core protein has been previously shown to circulate in the bloodstream of HCV-infected patients and inhibit host immunity through an interaction with gC1qR. Hepatitis C Virus is a positive, single stranded RNA virus in the Flaviviridae family. The genome is approximately 10,000 nucleotides and encodes a single polyprotein of about 3,000 amino acids. The polyprotein is processed by host cell and viral proteases into three major structural proteins and several non structural proteins necessary for viral replication. Hepatitis C virus (HCV) causes most cases of non-A, non-B hepatitis and results in most HCV infected people developing chronic infections, liver cirrhosis and hepatocellular carcinoma. T cell responses, including interferon-gamma production are severely suppressed in chronic HCV patients. -
细胞定位
Endoplasmic reticulum -
数据库链接
- SwissProt: P26664 Hepatitis C virus
- SwissProt: P29846 Hepatitis C virus
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别名
- Core protein p21 antibody
- HCV core antigen antibody
- HCV core protein antibody
- Hepatitis C Virus core protein antibody
数据表及文件
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Datasheet download
文献 (1)
ab2582 被引用在 1 文献中.
- Draz MS et al. Virus detection using nanoparticles and deep neural network-enabled smartphone system. Sci Adv 6:N/A (2020). PubMed: 33328239