Anti-Hepatitis C Virus抗体[NS5B-6] (FITC) (ab122979)

概述

  • 产品名称Anti-Hepatitis C Virus抗体[NS5B-6] (FITC)
    参阅全部 Hepatitis C Virus 一抗
  • 描述
    小鼠单克隆抗体[NS5B-6] to丙型肝炎病毒(FITC)
  • 偶联物FITC. Ex: 493nm, Em: 528nm
  • 特异性Specific to Human HCV NS5b protein of genotype 1b. Not tested in other genotypes.
  • 经测试应用适用于: WB, ELISA, ICC/IFmore details
  • 种属反应性
    与反应: Hepatitis C Virus
  • 免疫原

    A region of NS5b protein of Hepatitis C Virus genotype 1b expressed in E. coli.

  • 阳性对照
    • Chimp liver cells and cell lysate, infected with recombinant vaccinia virus containing a HCV genome cDNA.

性能

应用

Our Abpromise guarantee covers the use of ab122979 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use at an assay dependent concentration. Predicted molecular weight: 327 kDa.
ELISA Use at an assay dependent concentration.
ICC/IF Use at an assay dependent concentration.

靶标

  • 相关性Hepatitis C Virus is a positive, single stranded RNA virus in the Flaviviridae family. The genome is approximately 10,000 nucleotides and encodes a single polyprotein of about 3,000 amino acids. The polyprotein is processed by host cell and viral proteases into three major structural proteins and several non structural proteins necessary for viral replication. Several different genotypes of HCV with slightly different genomic sequences have since been identified that correlate with differences in response to treatment with interferon alpha.
  • 细胞定位Virus surface
  • 数据库链接
    • 别名
      • Genome polyprotein antibody
      • HCV antibody
      • Hepatitis C virus polyprotein antibody

    Anti-Hepatitis C Virus antibody [NS5B-6] (FITC) 图像

    • Anti-Hepatitis C Virus antibody [NS5B-6] (FITC) (ab122979) + Chimp liver cell lysate, infected with recombinant vaccinia virus containing a HCV genome cDNA

      Predicted band size : 327 kDa
      Observed band size : 58 kDa (why is the actual band size different from the predicted?)
    • ab122979, staining Hepatitis C Virus NS5b protein in Acetone-fixed Chimp liver cells infected with recombinant vaccinia virus containing a HCV genome cDNA by Immunofluorescence.

    Anti-Hepatitis C Virus antibody [NS5B-6] (FITC) (ab122979)参考文献

    This product has been referenced in:
    • Manabe S  et al. Production of nonstructural proteins of hepatitis C virus requires a putative viral protease encoded by NS3. Virology 198:636-44 (1994). Read more (PubMed: 8291245) »

    See 1 Publication for this product

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