Anti-Hepatitis B Virus Surface Antigen抗体(FITC) (ab21021)

概述

  • 产品名称Anti-Hepatitis B Virus Surface Antigen抗体(FITC)
    参阅全部 Hepatitis B Virus Surface Antigen 一抗
  • 描述
    兔多克隆抗体to乙型肝炎病毒Surface Antigen (FITC)
  • 偶联物FITC. Ex: 493nm, Em: 528nm
  • 特异性Monospecific, reacts only with Hepatitis B surface antigen including the pre-S1 epitope. This product is non-reactive with normal human serum.
  • 经测试应用适用于: ICC/IFmore details
  • 免疫原

    Hepatitis B surface antigen purified from human serum. Mixture of subtypes ad & ay.

  • 常规说明

    Covalently coupled with high purity Isomer I of fluorescein isothiocyanate. Care is taken to ensure complete removal of any free fluorescein from the final product.

性能

应用

Our Abpromise guarantee covers the use of ab21021 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC/IF
  • 应用说明Direct FA staining: Use at an assay dependent dilution. A starting range of 1:10-1:50 is suggested. Acetone fixation of the antigen source is recommended prior to staining.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性Hepatitis B Virus (HBV) infection induces a disease state which manifests itself in a variety of ways, characterized by the extent of liver damage, inflammation and viral persistence. HBV infection is also associated with a 100 fold increased risk of hepatocellular carcinoma and currently infects over 250 million people worldwide. HBV has a partially double stranded 3.2 kilobase DNA genome which contains four open reading frames. One of these encodes a 154 amino acid protein called the HBx protein. HBx has been shown to be a transcriptional transactivator of both viral and cellular promoters. Lacking a DNA binding domain and nuclear localization signal, HBx is believed to exert transcriptional activity through protein protein interaction.
    • 细胞定位Virion membrane
    • 别名
      • Large envelope protein antibody
      • Large surface protein antibody
      • LHB antibody
      • Major surface antigen antibody

    Anti-Hepatitis B Virus Surface Antigen antibody (FITC) (ab21021)参考文献

    ab21021 has not yet been referenced specifically in any publications.

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