Anti-Hepatitis B Virus Surface Antigen (Ad/Ay)抗体[S35] (ab20402)

概述

  • 产品名称Anti-Hepatitis B Virus Surface Antigen (Ad/Ay)抗体[S35]
    参阅全部 Hepatitis B Virus Surface Antigen (Ad/Ay) 一抗
  • 描述
    小鼠单克隆抗体[S35] to乙型肝炎病毒Surface Antigen (Ad/Ay)
  • 特异性Reacts with the ad and ay subtype of the Hepatitis B virus surface antigen.
  • 经测试应用适用于: ELISA, ICC/IF, Electron Microscopymore details
  • 免疫原

    HBsAg purified from human sera pool.

性能

应用

Our Abpromise guarantee covers the use of ab20402 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA Use at an assay dependent dilution.
ICC/IF Use at an assay dependent dilution.
Electron Microscopy Use at an assay dependent dilution.

靶标

  • 相关性Hepatitis B Virus (HBV) infection induces a disease state characterised by liver damage, inflammation and viral persistence. Infection also increases the risk of hepatocellular carcinoma. HBV belongs to the Hepadnaviridae family of viruses. Its genome consists of partially double stranded circular DNA. The DNA is enclosed in a nucleocapsid, or core antigen (HBcAg), which is surrounded by a spherical envelope (surface antigen or HBsAg). The core antigen shares its sequences with the e antigen (HBeAg) but no cross reactivity between the two proteins has been observed. The HBV genome also encodes a DNA polymerase that also acts as a reverse transcriptase. Hepatitis B infection is normally diagnosed from serological tests that detect HBsAg but as the disease progresses this antigen may no longer be present in the blood and tests for HBcAg are used. If HBsAg can be detected in the blood for longer than six months, chronic hepatitis B is diagnosed. The antigenic determinant of the protein moiety of the HBsAg determines specific characteristics of different serotypes and provides the basis of immunodetection. HBsAg has antigenic heterogeneity, specifically, two pairs of sub specific determinants, d/y and w/r allow the following combinations: adw, ayw, adr, ayr.
  • 细胞定位Virion membrane
  • 别名
    • HBsAg antibody
    • HBV major surface antigen antibody
    • HBV surface antigen antibody
    • Hepatitis B Virus major surface antigen antibody
    • Major surface antigen antibody
    • S antibody
    see all

Anti-Hepatitis B Virus Surface Antigen (Ad/Ay) antibody [S35] (ab20402)参考文献

ab20402 has not yet been referenced specifically in any publications.

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