Anti-Hepatitis B Virus Surface Antigen (Ad/Ay)抗体(HRP) (ab20878)

概述

  • 产品名称Anti-Hepatitis B Virus Surface Antigen (Ad/Ay)抗体(HRP)
    参阅全部 Hepatitis B Virus Surface Antigen (Ad/Ay) 一抗
  • 描述
    兔多克隆抗体to乙型肝炎病毒Surface Antigen (Ad/Ay) (HRP)
  • 偶联物HRP
  • 特异性Monospecific, reacts only with Hepatitis B surface antigen including the pre-S1 epitope. Non-reactive with normal human serum.
  • 经测试应用适用于: ELISAmore details
  • 种属反应性
    Monospecific, reacts only with Hepatitis B surface antigen including the pre-S1 epitope. Non-reactive with normal human serum.
  • 免疫原

    Hepatitis B surface antigen purified from human serum. Mixture of subtypes ad & ay.

  • 常规说明

    Estimated molar HRP:IgG substitution is 2-3.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C.
  • 存储溶液Preservative: 0.002% Thimerosal (merthiolate)
    Constituents: PBS, 10mg/ml BSA
  • Concentration information loading...
  • 纯度Protein A purified
  • 纯化说明Protein A chromatography purified IgG fraction covalently coupled to a highly purified preparation of horseradish peroxidase (RZ>3). Care is taken to ensure adequate conjugation while preserving maximum enzyme activity. Free enzyme is absent.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab20878 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA
  • 应用说明ELISA: Use at an assay dependent dilution.
    Suitability for use in Western blot, IHC and IFA has not been determined but use in such assays should not be excluded.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性Hepatitis B Virus (HBV) infection induces a disease state characterised by liver damage, inflammation and viral persistence. Infection also increases the risk of hepatocellular carcinoma. HBV belongs to the Hepadnaviridae family of viruses. Its genome consists of partially double stranded circular DNA. The DNA is enclosed in a nucleocapsid, or core antigen (HBcAg), which is surrounded by a spherical envelope (surface antigen or HBsAg). The core antigen shares its sequences with the e antigen (HBeAg) but no cross reactivity between the two proteins has been observed. The HBV genome also encodes a DNA polymerase that also acts as a reverse transcriptase. Hepatitis B infection is normally diagnosed from serological tests that detect HBsAg but as the disease progresses this antigen may no longer be present in the blood and tests for HBcAg are used. If HBsAg can be detected in the blood for longer than six months, chronic hepatitis B is diagnosed. The antigenic determinant of the protein moiety of the HBsAg determines specific characteristics of different serotypes and provides the basis of immunodetection. HBsAg has antigenic heterogeneity, specifically, two pairs of sub specific determinants, d/y and w/r allow the following combinations: adw, ayw, adr, ayr.
    • 细胞定位Virion membrane
    • 别名
      • HBsAg antibody
      • HBV major surface antigen antibody
      • HBV surface antigen antibody
      • Hepatitis B Virus major surface antigen antibody
      • Major surface antigen antibody
      • S antibody
      see all

    Anti-Hepatitis B Virus Surface Antigen (Ad/Ay) antibody (HRP) (ab20878)参考文献

    ab20878 has not yet been referenced specifically in any publications.

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